Protein Summary
May be involved in transcriptional regulation. Zinc finger proteins have been shown to interact with nucleic acids and to have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordinating zinc. Kruppel-related proteins form 1 family of zinc finger proteins. See ZFP93 (MIM 604749) for additional information on zinc finger proteins.[supplied by OMIM, Jul 2002]
- ENST00000357002
- ENSP00000349494
- ENSG00000213096
- BMZF5
- ZNF539
- ZNF91L
- BMZF-5
- ZNF539
- ZNF91L
- HD-ZNF1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
small molecule perturbation | 0.63 | ||
histone modification site profile | 0.61 | ||
protein domain | 0.58 | ||
tissue sample | 0.56 | ||
biological process | 0.52 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 38 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 38 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0