TBX10
T-box transcription factor TBX10
Protein Summary
Probable transcriptional regulator involved in developmental processes. This gene encodes a member of the T-box family of transcription factors. These transcription factors share a DNA-binding domain called the T-box, and play a role in several developmental processes including early embryonic cell fate and organogenesis. The encoded protein is a member of the T-box 1 subfamily. Mutations in this gene are thought to be a cause of isolated cleft lip with or without cleft palate. [provided by RefSeq, Nov 2010]
- ENST00000335385
- ENSP00000335191
- ENSG00000167800
- TBX7
- TBX7
- TBX13
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
cell line | 0.6 | ||
phenotype | 0.54 | ||
tissue | 0.52 | ||
biological process | 0.43 | ||
protein domain | 0.41 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 13.27 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 139 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 13.27 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 139 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0