LILRA1
Leukocyte immunoglobulin-like receptor subfamily A member 1
Protein Summary
May act as receptor for class I MHC antigens. This gene encodes an activating member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein is predominantly expressed in B cells, interacts with major histocompatibility complex class I ligands, and contributes to the regulation of immune responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
- ENST00000251372
- ENSP00000251372
- ENSG00000104974
- ENST00000453777
- ENSP00000413715
- ENST00000617170
- ENSP00000477637
- ENSG00000275525
- ENST00000620606
- ENSP00000478666
- ENST00000628480
- ENSP00000487229
- ENSG00000277398
- ENST00000631007
- ENSP00000487011
- ENSG00000274935
- LIR6
- LIR6
- CD85I
- LIR-6
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
co-expressed gene | 1 | ||
tissue sample | 0.73 | ||
cell line | 0.65 | ||
cell type or tissue | 0.62 | ||
protein domain | 0.58 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 5.19 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 175 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 5.19 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 175 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0