Property Summary

NCBI Gene PubMed Count 1,156
Grant Count 1,621
R01 Count 1,004
Funding $177,674,485.58
PubMed Score 3173.48
PubTator Score 1673.94

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Relevance (67)

Disease Z-score Confidence
periodontitis 269 5.171 2.6
tuberculosis 1,557 5.127 2.6
Inflammatory bowel disease 142 4.751 2.4
Pneumonia 133 4.706 2.4
Arthritis 248 4.481 2.2
Mastitis 48 4.463 2.2
Meningitis 46 4.451 2.2
Atherosclerosis 275 4.38 2.2
Asthma 349 4.284 2.1
Lyme disease 23 4.252 2.1
Allergic hypersensitivity disease 123 4.134 2.1
Tularemia 22 4.125 2.1
Dermatitis 107 4.071 2.0
Acne 20 4.032 2.0
Cancer 2,346 4.029 2.0
Leptospirosis 17 3.956 2.0
Otitis media 32 3.953 2.0
Keratitis 42 3.799 1.9
Leprosy 77 3.754 1.9
Leishmaniasis 49 3.731 1.9
Hypersensitivity reaction type II diseas... 235  3.703 1.9
Malaria 140 3.55 1.8
Candidiasis 48 3.544 1.8
diabetes mellitus 1,663 3.534 1.8
Influenza 142 3.518 1.8
Paracoccidioidomycosis 11 3.409 1.7
Chronic obstructive pulmonary disease 146 3.384 1.7
Peritonitis 37 3.367 1.7
Neurodegenerative disease 383 3.325 1.7
Chorioamnionitis 15 3.208 1.6
Bacterial vaginosis 15 3.184 1.6
Liver disease 219 3.154 1.6
Filariasis 21 3.145 1.6
Rosacea 18 3.144 1.6
Kidney disease 396 3.141 1.6
Perinatal necrotizing enterocolitis 18 3.116 1.6
Obesity 616 3.102 1.6
Common cold 63 3.095 1.5
Chlamydia 18 3.089 1.5
Human immunodeficiency virus infectious ... 92  3.088 1.5
cystic fibrosis 1,665 3.065 1.5
Melioidosis 11 3.052 1.5
Aspergillosis 23 3.051 1.5
Breast cancer 3,094
Cardiomyopathies 90
Colorectal Neoplasms 217
Eye Infections, Bacterial 2
IGA Glomerulonephritis 454
Inflammation 109
LEPROSY, SUSCEPTIBILITY TO, 3 1
MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILI... 12 
Reperfusion Injury 84
Rheumatoid Arthritis 1,160
Staphylococcal Infections 4
cutaneous lupus erythematosus 1,056
gastric carcinoma 832
glioblastoma 5,572
interstitial cystitis 2,299
invasive ductal carcinoma 2,950
lung cancer 4,466
lung carcinoma 2,844
medulloblastoma, large-cell 6,234
ovarian cancer 8,484
pilocytic astrocytoma 3,086
psoriasis 6,685
subependymal giant cell astrocytoma 2,287
ulcerative colitis 2,087

Expression

  Differential Expression (14)

Disease log2 FC p
cutaneous lupus erythematosus 1.700 0.002
psoriasis 1.100 0.003
glioblastoma 2.800 0.000
medulloblastoma, large-cell -1.100 0.001
lung cancer -3.200 0.000
interstitial cystitis 1.600 0.000
pilocytic astrocytoma 1.400 0.000
subependymal giant cell astrocytoma 2.381 0.008
invasive ductal carcinoma 1.197 0.005
lung carcinoma -2.700 0.000
Breast cancer -1.400 0.000
gastric carcinoma 1.200 0.027
ulcerative colitis 1.400 0.001
ovarian cancer -1.900 0.000

Synonym

Accession O60603 B3Y612 D1CS45 D1CS48 D1CS49 O15454 Q8NI00
Symbols TIL4
CD282

Gene

PANTHER Protein Class (1)

PDB

2Z7X   1FYW   1FYX   1O77   2Z80