| Tbio | Trafficking kinesin-binding protein 2 |
May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR.
Comments
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Liver Cirrhosis, Experimental | 769 | 0.0 | 0.0 |
| Disease | Target Count | P-value |
|---|---|---|
| lung adenocarcinoma | 2716 | 3.7e-17 |
| psoriasis | 6694 | 1.0e-06 |
| ulcerative colitis | 1819 | 2.2e-06 |
| ovarian cancer | 8520 | 8.1e-06 |
| Pick disease | 1894 | 2.7e-04 |
| osteosarcoma | 7950 | 6.0e-04 |
| Rheumatoid arthritis | 1191 | 9.5e-04 |
| atypical teratoid / rhabdoid tumor | 5112 | 5.1e-03 |
| subependymal giant cell astrocytoma | 2287 | 1.4e-02 |
| mucosa-associated lymphoid tissue lymphoma | 484 | 3.6e-02 |
| Disease | log2 FC | p |
|---|---|---|
| atypical teratoid / rhabdoid tumor | -1.100 | 5.1e-03 |
| lung adenocarcinoma | -1.100 | 3.7e-17 |
| mucosa-associated lymphoid tissue lympho... | 1.268 | 3.6e-02 |
| osteosarcoma | -1.371 | 6.0e-04 |
| ovarian cancer | -1.900 | 8.1e-06 |
| Pick disease | 1.400 | 2.7e-04 |
| psoriasis | -1.100 | 1.0e-06 |
| Rheumatoid arthritis | 1.200 | 9.5e-04 |
| subependymal giant cell astrocytoma | 1.291 | 1.4e-02 |
| ulcerative colitis | -1.100 | 2.2e-06 |
| Species | Source | Disease |
|---|---|---|
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA | ||
| OMA EggNOG |
MSQSQNAIFTSPTGEENLMNSNHRDSESITDVCSNEDLPEVELVSLLEEQLPQYRLKVDTLFLYENQDWT 1 - 70 QSPHQRQHASDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRN 71 - 140 HVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQL 141 - 210 EMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRY 211 - 280 QEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKEL 281 - 350 RSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDEESSLFKQKAQQKRVFDTVRIANDTRGRSIS 351 - 420 FPALLPIPGSNRSSVIMTAKPFESGLQQTEDKSLLNQGSSSEEVAGSSQKMGQPGPSGDSDLATALHRLS 421 - 490 LRRQNYLSEKQFFAEEWQRKIQVLADQKEGVSGCVTPTESLASLCTTQSEITDLSSASCLRGFMPEKLQI 491 - 560 VKPLEGSQTLYHWQQLAQPNLGTILDPRPGVITKGFTQLPGDAIYHISDLEEDEEEGITFQVQQPLEVEE 561 - 630 KLSTSKPVTGIFLPPITSAGGPVTVATANPGKCLSCTNSTFTFTTCRILHPSDITQVTPSSGFPSLSCGS 631 - 700 SGSSSSNTAVNSPALSYRLSIGESITNRRDSTTTFSSTMSLAKLLQERGISAKVYHSPISENPLQPLPKS 701 - 770 LAIPSTPPNSPSHSPCPSPLPFEPRVHLSENFLASRPAETFLQEMYGLRPSRNPPDVGQLKMNLVDRLKR 771 - 840 LGIARVVKNPGAQENGRCQEAEIGPQKPDSAVYLNSGSSLLGGLRRNQSLPVIMGSFAAPVCTSSPKMGV 841 - 910 LKED 911 - 914 //
