Property Summary

NCBI Gene PubMed Count 8
PubMed Score 0.00
PubTator Score 55.58

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (1)

Disease Target Count P-value
osteosarcoma 7933 5.49931574603593E-10
atypical teratoid / rhabdoid tumor 4369 4.21569968994156E-5
Pick disease 1893 6.95359639097308E-5
malignant mesothelioma 3163 3.82110070151051E-4
medulloblastoma 1524 0.00254107641242969
lung cancer 4473 0.0199147065957037

Expression

  Differential Expression (6)

Disease log2 FC p
malignant mesothelioma 1.200 0.000
osteosarcoma 4.055 0.000
atypical teratoid / rhabdoid tumor -1.400 0.000
medulloblastoma -1.300 0.003
lung cancer 1.400 0.020
Pick disease 1.200 0.000

Synonym

Accession O43716 B3KSU7 Q3B824 Q3KNR8 Glu-AdT subunit C
Symbols 15E1.2

Gene

  Ortholog (4)

Species Source
Chimp OMA EggNOG
Mouse OMA EggNOG
Rat OMA EggNOG
Cow OMA Inparanoid

Gene RIF (3)

PMID Text
24579914 The mitochondrial defective phenotype provoked by the absence of gatA in human cells is confirmed by means of a deficient ability to grow when galactose is used as a carbon source.
20877624 Observational study of gene-disease association. (HuGE Navigator)
19805282 Studies showed in vitro Gln-tRNA(Gln) formation catalyzed by the recombinant mtGluRS and hGatCAB.

AA Sequence

MWSRLVWLGLRAPLGGRQGFTSKADPQGSGRITAAVIEHLERLALVDFGSREAVARLEKAIAFADRLRAV      1 - 70
DTDGVEPMESVLEDRCLYLRSDNVVEGNCADELLQNSHRVVEEYFVAPPGNISLPKLDEQEPFPHS         71 - 136
//

Text Mined References (8)

PMID Year Title
25416956 2014 A proteome-scale map of the human interactome network.
24579914 2014 Glutamyl-tRNAGln amidotransferase is essential for mammalian mitochondrial translation in vivo.
20877624 2010 Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
19805282 2009 Biogenesis of glutaminyl-mt tRNAGln in human mitochondria.
16541075 2006 The finished DNA sequence of human chromosome 12.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.