Property Summary

NCBI Gene PubMed Count 76
PubMed Score 146.26
PubTator Score 124.16

Knowledge Summary


No data available


  Disease Sources (3)

Disease Target Count P-value
psoriasis 6685 2.18180007080816E-94
lung carcinoma 2844 4.11716215773154E-23
ovarian cancer 8492 2.78944910199588E-16
non-small cell lung cancer 2798 1.31815517287098E-13
Atopic dermatitis 944 1.53216937482183E-7
lung adenocarcinoma 2714 8.85063521550513E-6
tuberculosis and treatment for 3 months 327 1.08743299699805E-4
ulcerative colitis 2087 4.34959911448031E-4
interstitial cystitis 2299 0.00122801824473324
oligodendroglioma 2849 0.00279283148801132
lung cancer 4473 0.00531935153575966
pancreatic cancer 2300 0.00562128848782013
pancreatic carcinoma 567 0.00562128848782015
mucosa-associated lymphoid tissue lymphoma 480 0.00889725770630438
invasive ductal carcinoma 2950 0.014124287283322
group 3 medulloblastoma 2254 0.0175359733375966
pancreatic ductal adenocarcinoma liver metastasis 1795 0.0236889076064208


  Differential Expression (17)


Accession O43315 Q9NP32 AQP-9
Symbols SSC1


PANTHER Protein Class (1)

  Ortholog (10)

Gene RIF (46)

26837049 Our findings implicate the involvement of AQP9 in H2O2 transport in human and mice cells.
26313002 the human aquaglyceroporins, i.e., AQP3, AQP7, AQP9 and AQP10 can act as silicon transporters in both Xenopus laevis oocytes and HEK-293 cells.
25604497 we suggest that AQP9 is involved in viral tropism and pathogenesis of Herpes simplex encephalitis
25105540 Oleic acid-induced hepatic steatosis in HepG2 cells is associated with the coordinated regulation of aquaporin 3 and aquaporin 9 via activation of p38 signaling
24643204 The genetic polymorphisms in OCT2, AQP2, AQP9 and TMEM205 may contribute to chemotherapy response in lung cancer patients.
24463099 REVIEW: the current knowledge on the role of the glycerol channels AQP7 and AQP9 in controlling glycerol metabolism in adipose tissue and liver
24418844 AQP9 downregulation together with the subsequent reduction in hepatic glycerol permeability in insulin-resistant states emerges as a compensatory mechanism whereby the liver counteracts further triacylglycerol accumulation
24086629 AQP9 expressing glioma cells were negative for the brain tumor stem cell marker CD15.
23866971 Placental expression of the arsenic transporter AQP9 was positively associated with maternal urinary arsenic levels during pregnancy. AQP9 expression related to phospholipase ENPP2 expression which was positively associated with infant birth weight.
23612070 AQP9 expression is lower in patients with stage III colorectal cancer who do not respond to adjuvant chemotherapy

AA Sequence

QSEDKPEKYELSVIM                                                           281 - 295

Text Mined References (77)

PMID Year Title
26837049 2016 Aquaporin-9 facilitates membrane transport of hydrogen peroxide in mammalian cells.
26313002 2015 Aquaporins Mediate Silicon Transport in Humans.
25604497 2015 The anterior commissure is a pathway for contralateral spread of herpes simplex virus type 1 after olfactory tract infection.
25105540 2015 Oleic acid-induced hepatic steatosis is coupled with downregulation of aquaporin 3 and upregulation of aquaporin 9 via activation of p38 signaling.
24643204 2014 The association of transporter genes polymorphisms and lung cancer chemotherapy response.
24463099 2014 Metabolic impact of the glycerol channels AQP7 and AQP9 in adipose tissue and liver.
24418844 2014 Reduced hepatic aquaporin-9 and glycerol permeability are related to insulin resistance in non-alcoholic fatty liver disease.
24086629 2013 AQP9 expression in glioblastoma multiforme tumors is limited to a small population of astrocytic cells and CD15(+)/CalB(+) leukocytes.
23866971 2013 Association between In Utero arsenic exposure, placental gene expression, and infant birth weight: a US birth cohort study.
23612070 2013 Multi-microarray identifies lower AQP9 expression in adjuvant chemotherapy nonresponders with stage III colorectal cancer.