Property Summary

NCBI Gene PubMed Count 14
Grant Count 2
Funding $229,280.67
PubMed Score 53.79
PubTator Score 3.42

Knowledge Summary


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Gene RIF (4)

23593011 we describe an example where two lncRNA genes (DLEU1 and DLEU2) are epigenetically deregulated together with a cluster of neighboring protein-coding tumor suppressor genes in almost all patients suffering from chronic lymphocytic leukemia
19347735 propose that the underlying pathomechanism of CLL involves co-regulation of miRNA genes miR-16-1 and miR-15a by the two long non-coding RNA genes DLEU1 and DLEU2.
19260139 Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
11406609 Leu1 seems to be only one of the smallest splicing variants of a large gene termed BCMS.

AA Sequence

EIDDSIFY                                                                   71 - 78

Text Mined References (16)

PMID Year Title
23593011 2013 Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the In Cis downregulation of a gene cluster that targets NF-kB.
22424883 2012 Genome-wide association study of lung function decline in adults with and without asthma.
22190364 2011 Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.
21833088 2011 Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
20351715 2011 Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.
20190752 2010 Multiple common variants for celiac disease influencing immune gene expression.
19347735 2009 Chronic lymphocytic leukemia and 13q14: miRs and more.
19260139 2009 Genome-wide association study of anthropometric traits in Korcula Island, Croatia.
16751776 2006 A germline-specific class of small RNAs binds mammalian Piwi proteins.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).