Property Summary

NCBI Gene PubMed Count 21
Grant Count 10
Funding $600,926.24
PubMed Score 11.52
PubTator Score 8.33

Knowledge Summary

Patent

No data available

Expression

Gene RIF (2)

PMID Text
22378351 Levels of ARPC5 expression were significantly higher in invasive cancer cells and gene expression was directly regulated by miR-133a.
12829704 identified as a substrate of MAPK-activated protein kinase 2(MAPKAPK2); the ability of MAPKAPK2 to phosphorylate one isoform of p16-Arc suggests a possible mechanism by which the p38 MAPK cascade regulates remodeling of the actin cytoskeleton

AA Sequence

MSKNTVSSARFRKVDVDEYDENKFVDEEDGGDGQAGPDEGEVDSCLRQGNMTAALQAALKNPPINTKSQA      1 - 70
VKDRAGSIVLKVLISFKANDIEKAVQSLDKNGVDLLMKYIYKGFESPSDNSSAMLLQWHEKALAAGGVGS     71 - 140
IVRVLTARKTV                                                               141 - 151
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Text Mined References (26)

PMID Year Title
25944712 2015 N-terminome analysis of the human mitochondrial proteome.
24275569 2014 An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
23376485 2013 Proteomic analysis of podocyte exosome-enriched fraction from normal human urine.
22814378 2012 N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
22378351 2012 Actin-related protein 2/3 complex subunit 5 (ARPC5) contributes to cell migration and invasion and is directly regulated by tumor-suppressive microRNA-133a in head and neck squamous cell carcinoma.
22089643 2012 Tumor suppressive microRNA-133a regulates novel molecular networks in lung squamous cell carcinoma.
22016387 2011 GRAIL (gene related to anergy in lymphocytes) regulates cytoskeletal reorganization through ubiquitination and degradation of Arp2/3 subunit 5 and coronin 1A.
21423176 2011 Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for ?-Pix in negative regulation of focal adhesion maturation.
21281821 2011 Rear polarization of the microtubule-organizing center in neointimal smooth muscle cells depends on PKC?, ARPC5, and RHAMM.
21269460 2011 Initial characterization of the human central proteome.
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