Property Summary

NCBI Gene PubMed Count 17
PubMed Score 7.03
PubTator Score 11.06

Knowledge Summary


No data available


  Differential Expression (11)

Disease log2 FC p
osteosarcoma 1.811 3.0e-03
glioblastoma 1.500 1.1e-02
atypical teratoid / rhabdoid tumor -1.100 7.1e-05
medulloblastoma, large-cell -1.100 6.7e-04
pancreatic ductal adenocarcinoma liver m... -1.984 2.1e-02
non-small cell lung cancer 1.298 3.2e-18
adult high grade glioma -1.100 3.6e-03
lung adenocarcinoma 1.012 2.5e-03
invasive ductal carcinoma 1.100 2.0e-03
ovarian cancer 1.300 1.8e-03
Breast cancer 1.100 1.3e-04

Gene RIF (5)

20877624 Observational study of gene-disease association. (HuGE Navigator)
19439209 NF-Y type CCAAT boxes are found preferentially in bidirectional Mrps12/Sarsm promoters, but many such promoters lack them and must be regulated in another way.
18854154 Knockdown of mitochondrial ribosomal protein S12 (MRPS12) by siRNA inhibits the early stages of HIV-1 replication in 293T cells infected with VSV-G pseudotyped HIV-1
18790094 mitochondrial ribosomal protein S12 3'-UTR interacts specifically with TRAP1 (tumor necrosis factor receptor-associated protein1), hnRNPM4 (heterogeneous nuclear ribonucleoprotein M4), Hsp70 and Hsp60 (heat shock proteins 70 and 60), and alpha-tubulin
12706105 Homo sapiens mitochondrial ribosomal protein S12

AA Sequence


Text Mined References (19)

PMID Year Title
25944712 2015 N-terminome analysis of the human mitochondrial proteome.
22681889 2012 The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
21269460 2011 Initial characterization of the human central proteome.
20877624 2010 Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
19439209 2009 NF-Y influences directionality of transcription from the bidirectional Mrps12/Sarsm promoter in both mouse and human cells.
18790094 2008 cis-acting sequences and trans-acting factors in the localization of mRNA for mitochondrial ribosomal proteins.
16169070 2005 A human protein-protein interaction network: a resource for annotating the proteome.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
12970870 2003 Using yeast two-hybrid system to identify ECRG2 associated proteins and their possible interactions with ECRG2 gene.
12706105 2003 Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome.
12646258 2003 ECRG2, a novel candidate of tumor suppressor gene in the esophageal carcinoma, interacts directly with metallothionein 2A and links to apoptosis.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
11543634 2001 The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders.
11402041 2001 Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28 S small subunit.
11279123 2001 The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present.
10542210 1999 Expression of the gene for mitoribosomal protein S12 is controlled in human cells at the levels of transcription, RNA splicing, and translation.
9790755 1998 Characterization of the human mitochondrial ribosomal S12 gene.
9545647 1998 Chromosomal locations of three human nuclear genes (RPSM12, TUFM, and AFG3L1) specifying putative components of the mitochondrial gene expression apparatus.
9434165 1997 Metazoan nuclear genes for mitoribosomal protein S12.