Property Summary

NCBI Gene PubMed Count 13
Grant Count 5
R01 Count 5
Funding $912,859
PubMed Score 28.50
PubTator Score 5.85

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Relevance (3)

Expression

  Differential Expression (2)

Disease log2 FC p
Waldenstrons macroglobulinemia 1.081 0.007
ovarian cancer -1.100 0.001

Synonym

Accession O14950 D3DUH6 Q13182 Q7Z5Z4
Symbols MLCB
MRCL3
MRLC3
MYL2B
MLC-2B
HEL-S-24

Gene

Gene RIF (1)

PMID Text
19794400 Treatment of human brain endothelial cells with Tat markedly elevates GTP-RhoA levels and the potential downstream effectors, such as myosin phosphatase target subunit 1 and myosin light chain

AA Sequence

MSSKKAKTKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYL      1 - 70
DAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVD     71 - 140
ELYREAPIDKKGNFNYIEFTRILKHGAKDKDD                                          141 - 172
//

Text Mined References (22)

PMID Year Title
24275569 2014 An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
23382103 2013 Platelet proteome analysis reveals integrin-dependent aggregation defects in patients with myelodysplastic syndromes.
23376485 2013 Proteomic analysis of podocyte exosome-enriched fraction from normal human urine.
22909821 2012 AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis.
21457715 2011 Chelerythrine perturbs lamellar actomyosin filaments by selective inhibition of myotonic dystrophy kinase-related Cdc42-binding kinase.
20458337 MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
18480596 2008 Smooth muscle type isoform of 20 kDa myosin light chain is expressed in monocyte/macrophage cell lineage.
17719568 2007 Subtractive hybridisation screen identifies genes regulated by glucose deprivation in human neuroblastoma cells.
17353931 2007 Large-scale mapping of human protein-protein interactions by mass spectrometry.
17126281 2006 Novel ZIP kinase isoform lacks leucine zipper.
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