| Tbio | Cytochrome b-c1 complex subunit 8 |
This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit, together with cytochrome b, binds to ubiquinone.
This gene encodes a ubiquinone-binding protein of low molecular mass. This protein is a small core-associated protein and a subunit of ubiquinol-cytochrome c reductase complex III, which is part of the mitochondrial respiratory chain. [provided by RefSeq, Jul 2008]
This gene encodes a ubiquinone-binding protein of low molecular mass. This protein is a small core-associated protein and a subunit of ubiquinol-cytochrome c reductase complex III, which is part of the mitochondrial respiratory chain. [provided by RefSeq, Jul 2008]
Comments
| Disease | log2 FC | p |
|---|---|---|
| Multiple myeloma | 1.302 | 0.001 |
| lung cancer | 1.400 | 0.000 |
| ovarian cancer | 1.900 | 0.000 |
| PMID | Text |
|---|---|
| 25950827 | QP-C protein gene expression involved in the development of hyperpigmentation. |
| 20877624 | Observational study of gene-disease association. (HuGE Navigator) |
| 20440543 | Decreased electron Transport Complex III activity is associated with ulcerative colitis. |
| 18439546 | We thus suggest that a homozygous mutation in UQCRQ is associated with defective function of mitochondrial complex III, leading to a severe autosomal-recessive neurological phenotype. |
| PMID | Year | Title |
|---|---|---|
| 25950827 | 2015 | Identification of Genes Expressed in Hyperpigmented Skin Using Meta-Analysis of Microarray Data Sets. |
| 25944712 | 2015 | N-terminome analysis of the human mitochondrial proteome. |
| 23186163 | 2013 | Toward a comprehensive characterization of a human cancer cell phosphoproteome. |
| 21269460 | 2011 | Initial characterization of the human central proteome. |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. |
| 20440543 | 2010 | Mitochondrial respiratory chain in the colonic mucosal of patients with ulcerative colitis. |
| 18439546 | 2008 | Mitochondrial complex III deficiency associated with a homozygous mutation in UQCRQ. |
| 15544925 | 2004 | Oxidative modification of mitochondrial respiratory complexes in response to the stress of Trypanosoma cruzi infection. |
| 15489334 | 2004 | The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
| 12477932 | 2002 | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |
| More... |
