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Tbio
DPYSL4
Dihydropyrimidinase-related protein 4

Protein Summary
Description
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000338492
  • ENSP00000339850
  • ENSG00000151640

Symbol
  • CRMP3
  • ULIP4
  • CRMP3
  • DRP-4
  • ULIP4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.8
transcription factor perturbation
0.8
disease perturbation
0.68
transcription factor
0.57
small molecule perturbation
0.52


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.62   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 196   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.62   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 196   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0