Property Summary

NCBI Gene PubMed Count 22
Grant Count 4
Funding $166,957.66
PubMed Score 30.51
PubTator Score 37.56

Knowledge Summary

Patent

No data available

Expression

Gene RIF (9)

PMID Text
26008593 This is the first research investigating the utility of TTTY15-USP9Y in prostate cancer detection
23650841 An impact of the identified polymorphism on discrimination of alleles of the M46 locus with various techniques was discussed, and solutions ensuring correctness of the genotyping results were proposed.
18511697 Observational study of gene-disease association. (HuGE Navigator)
18357961 Frequency of AZF microdeletions in peripheral leukocytes and testicular cells in Chinese men with idiopathic infertility.
18205040 rare Y chromosome missense mutation in exon 25 of human USP9Y revealed by pyrosequencing
15696490 Findings indicated that AZF microdeletion and chromosomal abnormality should be important causes of male infertility.
12925892 Selection is acting to maintain the amino acid sequence of both the X and the Y-linked genes.
12895410 results suggest that, through de-ubiquitination, ubiquitin specific protease 9(USP9Y) may stabilize a specific target protein that is important for male germ cell development
11869379 detection of mrna in azooermic men

AA Sequence

MTAITHGSPVGGNDSQGQVLDGQSQHLFQQNQTSSPDSSNENSVATPPPEEQGQGDAPPQHEDEEPAFPH      1 - 70
TELANLDDMINRPRWVVPVLPKGELEVLLEAAIDLSVKGLDVKSEACQRFFRDGLTISFTKILMDEAVSG     71 - 140
WKFEIHRCIINNTHRLVELCVAKLSQDWFPLLELLAMALNPHCKFHIYNGTRPCELISSNAQLPEDELFA    141 - 210
RSSDPRSPKGWLVDLINKFGTLNGFQILHDRFFNGSALNIQIIAALIKPFGQCYEFLSQHTLKKYFIPVI    211 - 280
EIVPHLLENLTDEELKKEAKNEAKNDALSMIIKSLKNLASRISGQDETIKNLEIFRLKMILRLLQISSFN    281 - 350
GKMNALNEINKVISSVSYYTHRHSNPEEEEWLTAERMAEWIQQNNILSIVLQDSLHQPQYVEKLEKILRF    351 - 420
VIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPGQLDHLFDCFKASWTNASKKQREKLLE    421 - 490
LIRRLAEDDKDGVMAHKVLNLLWNLAQSDDVPVDIMDLALSAHIKILDYSCSQDRDAQKIQWIDHFIEEL    491 - 560
RTNDKWVIPALKQIREICSLFGEASQNLSQTQRSPHIFYRHDLINQLQQNHALVTLVAENLATYMNSIRL    561 - 630
YAGDHEDYDPQTVRLGSRYSHVQEVQERLNFLRFLLKDGQLWLCAPQAKQIWKCLAENAVYLCDREACFK    631 - 700
WYSKLMGDEPDLDPDINKDFFESNVLQLDPSLLTENGMKCFERFFKAVNCRERKLIAKRRSYMMDDLELI    701 - 770
GLDYLWRVVIQSSDEIANRAIDLLKEIYTNLGPRLKANQVVIHEDFIQSCFDRLKASYDTLCVFDGDKNS    771 - 840
INCARQEAIRMVRVLTVIKEYINECDSDYHKERMILPMSRAFRGKHLSLIVRFPNQGRQVDELDIWSHTN    841 - 910
DTIGSVRRCIVNRIKANVAHKKIELFVGGELIDSEDDRKLIGQLNLKDKSLITAKLTQINFNMPSSPDSS    911 - 980
SDSSTASPGNHRNHYNDGPNLEVESCLPGVIMSVHPRYISFLWQVADLGSNLNMPPLRDGARVLMKLMPP    981 - 1050
DRTAVEKLRAVCLDHAKLGEGKLSPPLDSLFFGPSASQVLYLTEVVYALLMPAGVPLTDGSSDFQVHFLK   1051 - 1120
SGGLPLVLSMLIRNNFLPNTDMETRRGAYLNALKIAKLLLTAIGYGHVRAVAEACQPVVDGTDPITQINQ   1121 - 1190
VTHDQAVVLQSALQSIPNPSSECVLRNESILLAQEISNEASRYMPDICVIRAIQKIIWASACGALGLVFS   1191 - 1260
PNEEITKIYQMTTNGSNKLEVEDEQVCCEALEVMTLCFALLPTALDALSKEKAWQTFIIDLLLHCPSKTV   1261 - 1330
RQLAQEQFFLMCTRCCMGHRPLLFFITLLFTILGSTAREKGKYSGDYFTLLRHLLNYAYNGNINIPNAEV   1331 - 1400
LLVSEIDWLKRIRDNVKNTGETGVEEPILEGHLGVTKELLAFQTSEKKYHFGCEKGGANLIKELIDDFIF   1401 - 1470
PASKVYLQYLRSGELPAEQAIPVCSSPVTINAGFELLVALAIGCVRNLKQIVDCLTEMYYMGTAITTCEA   1471 - 1540
LTEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSE   1541 - 1610
SNVDPRDDVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGFWKQFRLWGEPV   1611 - 1680
NLREQHDALEFFNSLVDSLDEALKALGHPAILSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQ   1681 - 1750
NLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVLAIQLKRFDYDWERECAIKFNDYFEF   1751 - 1820
PRELDMGPYTVAGVANLERDNVNSENELIEQKEQSDNETAGGTKYRLVGVLVHSGQASGGHYYSYIIQRN   1821 - 1890
GKDDQTDHWYKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYEQMDM   1891 - 1960
IDEDDEMIRYISELTIARPHQIIMSPAIERSVRKQNVKFMHNRLQYSLEYFQFVKKLLTCNGVYLNPAPG   1961 - 2030
QDYLLPEAEEITMISIQLAARFLFTTGFHTKKIVRGPASDWYDALCVLLRHSKNVRFWFTHNVLFNVSNR   2031 - 2100
FSEYLLECPSAEVRGAFAKLIVFIAHFSLQDGSCPSPFASPGPSSQACDNLSLSDHLLRATLNLLRREVS   2101 - 2170
EHGHHLQQYFNLFVMYANLGVAEKTQLLKLNVPATFMLVSLDEGPGPPIKYQYAELGKLYSVVSQLIRCC   2171 - 2240
NVSSTMQSSINGNPPLPNPFGDLNLSQPIMPIQQNVLDILFVRTSYVKKIIEDCSNSEDTIKLLRFCSWE   2241 - 2310
NPQFSSTVLSELLWQVAYSYTYELRPYLDLLFQILLIEDSWQTHRIHNALKGIPDDRDGLFDTIQRSKNH   2311 - 2380
YQKRAYQCIKCMVALFSSCPVAYQILQGNGDLKRKWTWAVEWLGDELERRPYTGNPQYSYNNWSPPVQSN   2381 - 2450
ETANGYFLERSHSARMTLAKACELCPEEEPDDQDAPDEHEPSPSEDAPLYPHSPASQYQQNNHVHGQPYT   2451 - 2520
GPAAHHLNNPQKTGQRTQENYEGNEEVSSPQMKDQ                                      2521 - 2555
//

Text Mined References (23)

PMID Year Title
26162009 2015 Isoform-Level Gene Expression Profiles of Human Y Chromosome Azoospermia Factor Genes and Their X Chromosome Paralogs in the Testicular Tissue of Non-Obstructive Azoospermia Patients.
26008593 2015 Clinical utility of a novel urine-based gene fusion TTTY15-USP9Y in predicting prostate biopsy outcome.
23650841 [Identification of a novel Y-SNP in the USP9Y gene and its impact on genotyping alleles of the M46 locus].
19246359 2009 Spermatogenesis in a man with complete deletion of USP9Y.
18511697 2008 Genetic variants of Y chromosome are associated with a protective lipid profile in black men.
18357961 AZF gene expression analysis in peripheral leukocytes and testicular cells from idiopathic infertility.
18205040 2008 A rare Y chromosome missense mutation in exon 25 of human USP9Y revealed by pyrosequencing.
16893908 2006 Natural transmission of USP9Y gene mutations: a new perspective on the role of AZFa genes in male fertility.
15696490 2005 [A genetic study on microdeletion of azoospermia factor region on Y chromosome of azoospermia and oligozoospermia patients].
14983005 2004 Protein structure prediction for the male-specific region of the human Y chromosome.
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