Tchem P2RY10 Putative P2Y purinoceptor 10

Protein Summary

Description

Putative receptor for purines coupled to G-proteins. The protein encoded by this gene belongs to the family of G-protein coupled receptors that are preferentially activated by adenosine and uridine nucleotides. There is a pseudogene for this gene nearby on chromosome X. Multiple alternatively spliced transcripts have been observed. [provided by RefSeq, Apr 2016]

Uniprot Accession IDs

• O00398
• D3DTE5
• Q4VBN7
• Q86V16
• P2Y10

Gene Name

• P2RY10

Ensembl ID

• ENST00000171757
• ENSP00000171757
• ENSG00000078589
• ENST00000544091
• ENSP00000443138

Symbol

• P2Y10
• LYPSR2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
co-expressed gene	1
cell type or tissue	0.78
gene perturbation	0.68
tissue sample	0.55
tissue	0.45

Protein Classes

DTO Classes

Protein / G-protein Coupled Receptor / Class A Rhodopsin Like / Purinoceptor / P2y Receptor / Putative P2y Purinoceptor 10

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.04   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 150   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.04   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 150   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 28

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0