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Tdark
NYAP1
Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1

Protein Summary
Description
Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000300179
  • ENSP00000300179
  • ENSG00000166924

Symbol
  • C7orf51
  • C7orf51
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.68
cellular component
0.64
histone modification site profile
0.63
transcription factor
0.57
tissue
0.55


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.75   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 8   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.75   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 8   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0