Tbio NRBP2 Nuclear receptor-binding protein 2

Protein Summary

Description

May regulate apoptosis of neural progenitor cells during their differentiation.

Uniprot Accession IDs

• Q9NSY0
• B4DF59
• Q2HIX8
• Q597G7
• Q8NCX8
• Q8WYS5

Gene Name

• NRBP2

Ensembl ID

• ENST00000442628
• ENSP00000414055
• ENSG00000185189

Symbol

• TRG16
• pp9320

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.88
histone modification site profile	0.72
virus perturbation	0.68
microRNA	0.57
cell line	0.54

Protein Classes

PANTHER Classes

Protein / Transferase / Kinase / Protein Kinase / Non-receptor Serine/threonine Protein Kinase / Nuclear Receptor-binding Protein 2

DTO Classes

Protein / Kinase / Protein Kinase / Other Group / Nrbp Family / Nuclear Receptor-binding Protein 2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.39   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 179   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.39   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 179   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0