Tbio NLGN4Y Neuroligin-4, Y-linked

Protein Summary

Description

Putative neuronal cell surface protein involved in cell-cell-interactions. This gene encodes a type I membrane protein that belongs to the family of neuroligins, which are cell adhesion molecules present at the postsynaptic side of the synapse, and may be essential for the formation of functional synapses. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Mar 2011]

Uniprot Accession IDs

• Q8NFZ3
• F5H6W0
• Q14D08
• Q7Z3T5
• Q8N5B6
• Q9Y2F8
• Neuroligin Y

Gene Name

• NLGN4Y

Ensembl ID

• ENST00000339174
• ENSP00000342535
• ENSG00000165246
• ENST00000355905
• ENSP00000348169
• ENST00000382872
• ENSP00000372325

Symbol

• KIAA0951
• HNL4Y

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.73
virus perturbation	0.72
microRNA	0.6
cell type or tissue	0.56
kinase perturbation	0.48

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 132   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 132   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 13

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0