You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
NEURL1B
E3 ubiquitin-protein ligase NEURL1B

Protein Summary
Description
E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000369800
  • ENSP00000358815
  • ENSG00000214357
  • ENST00000520919
  • ENSP00000429797
  • ENST00000522853
  • ENSP00000430001

Symbol
  • NEURL3
  • neur2
  • NEURL3
  • RNF67B
  • hNeur2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.76
microRNA
0.71
pathway
0.62
PubMedID
0.6
tissue sample
0.58


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.23   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 41   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.23   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 41   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0