Tdark | Adaptin ear-binding coat-associated protein 2 |
Involved in endocytosis.
This gene likely encodes a member of the adaptin-ear-binding coat-associated protein family. Studies of a similar protein in rat suggest a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]
This gene likely encodes a member of the adaptin-ear-binding coat-associated protein family. Studies of a similar protein in rat suggest a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]
Comments
Disease | Target Count | P-value |
---|---|---|
lung carcinoma | 2843 | 6.3e-25 |
astrocytoma | 1146 | 6.8e-21 |
ependymoma | 4679 | 7.5e-16 |
ovarian cancer | 8520 | 4.5e-10 |
Astrocytoma, Pilocytic | 3081 | 2.3e-07 |
adult high grade glioma | 3801 | 4.9e-04 |
glioblastoma | 5792 | 8.7e-04 |
dermatomyositis | 966 | 2.6e-03 |
subependymal giant cell astrocytoma | 2287 | 7.5e-03 |
Disease | Target Count | Z-score | Confidence |
---|---|---|---|
Cataract 8 multiple types | 33 | 4.264 | 2.1 |
Disease | log2 FC | p |
---|---|---|
adult high grade glioma | 1.200 | 4.9e-04 |
astrocytoma | 1.200 | 6.8e-21 |
Astrocytoma, Pilocytic | 1.200 | 2.3e-07 |
dermatomyositis | 1.100 | 2.6e-03 |
ependymoma | 1.500 | 7.5e-16 |
glioblastoma | 1.500 | 8.7e-04 |
lung carcinoma | -1.100 | 6.3e-25 |
ovarian cancer | -1.500 | 4.5e-10 |
subependymal giant cell astrocytoma | 1.407 | 7.5e-03 |
Species | Source | Disease |
---|---|---|
Inparanoid OMA EggNOG | ||
OMA EggNOG | ||
Inparanoid OMA EggNOG | ||
Inparanoid OMA EggNOG | ||
Inparanoid OMA EggNOG | ||
Inparanoid OMA EggNOG | ||
Inparanoid OMA EggNOG | ||
Inparanoid OMA | ||
Inparanoid OMA EggNOG | ||
Inparanoid OMA | ||
Inparanoid OMA EggNOG | ||
OMA EggNOG |
MEESGYESVLCVKPDVHVYRIPPRATNRGYRAAEWQLDQPSWSGRLRITAKGQMAYIKLEDRTSGELFAQ 1 - 70 APVDQFPGTAVESVTDSSRYFVIRIEDGNGRRAFIGIGFGDRGDAFDFNVALQDHFKWVKQQCEFAKQAQ 71 - 140 NPDQGPKLDLGFKEGQTIKLNIANMKKKEGAAGNPRVRPASTGGLSLLPPPPGGKTSTLIPPPGEQLAVG 141 - 210 GSLVQPAVAPSSGGAPVPWPQPNPATADIWGDFTKSTGSTSSQTQPGTGWVQF 211 - 263 //