| Tdark | Adaptin ear-binding coat-associated protein 2 |
Involved in endocytosis.
This gene likely encodes a member of the adaptin-ear-binding coat-associated protein family. Studies of a similar protein in rat suggest a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]
This gene likely encodes a member of the adaptin-ear-binding coat-associated protein family. Studies of a similar protein in rat suggest a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]
Comments
| Disease | Target Count | P-value |
|---|---|---|
| lung carcinoma | 2843 | 6.3e-25 |
| astrocytoma | 1146 | 6.8e-21 |
| ependymoma | 4679 | 7.5e-16 |
| ovarian cancer | 8520 | 4.5e-10 |
| Astrocytoma, Pilocytic | 3081 | 2.3e-07 |
| adult high grade glioma | 3801 | 4.9e-04 |
| glioblastoma | 5792 | 8.7e-04 |
| dermatomyositis | 966 | 2.6e-03 |
| subependymal giant cell astrocytoma | 2287 | 7.5e-03 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Cataract 8 multiple types | 33 | 4.264 | 2.1 |
| Disease | log2 FC | p |
|---|---|---|
| adult high grade glioma | 1.200 | 4.9e-04 |
| astrocytoma | 1.200 | 6.8e-21 |
| Astrocytoma, Pilocytic | 1.200 | 2.3e-07 |
| dermatomyositis | 1.100 | 2.6e-03 |
| ependymoma | 1.500 | 7.5e-16 |
| glioblastoma | 1.500 | 8.7e-04 |
| lung carcinoma | -1.100 | 6.3e-25 |
| ovarian cancer | -1.500 | 4.5e-10 |
| subependymal giant cell astrocytoma | 1.407 | 7.5e-03 |
MEESGYESVLCVKPDVHVYRIPPRATNRGYRAAEWQLDQPSWSGRLRITAKGQMAYIKLEDRTSGELFAQ 1 - 70 APVDQFPGTAVESVTDSSRYFVIRIEDGNGRRAFIGIGFGDRGDAFDFNVALQDHFKWVKQQCEFAKQAQ 71 - 140 NPDQGPKLDLGFKEGQTIKLNIANMKKKEGAAGNPRVRPASTGGLSLLPPPPGGKTSTLIPPPGEQLAVG 141 - 210 GSLVQPAVAPSSGGAPVPWPQPNPATADIWGDFTKSTGSTSSQTQPGTGWVQF 211 - 263 //
