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Tbio Nucleosome assembly protein 1-like 3

This gene is intronless and encodes a member of the nucleosome assembly protein (NAP) family. This gene is linked closely to a region of genes responsible for several X-linked cognitive disability syndromes. [provided by RefSeq, Dec 2010]

 Comments

Property Summary

NCBI Gene PubMed Count 7
PubMed Score 11.83
PubTator Score 14.78

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (3)

Disease Target Count Z-score Confidence
Carcinoma 11493 0.0 0.9
Kidney cancer 2613 0.0 0.5
Disease Target Count Z-score Confidence
Tangier disease 10 3.177 1.6

Expression

  Differential Expression (23)

Disease log2 FC p
acute myeloid leukemia -1.300 1.8e-03
adult high grade glioma -2.500 8.0e-06
aldosterone-producing adenoma -1.397 2.9e-02
astrocytoma -1.200 2.0e-11
Atopic dermatitis -1.700 4.6e-04
atypical teratoid / rhabdoid tumor -3.500 5.3e-06
Breast cancer -2.100 1.6e-13
colon cancer -1.900 6.3e-05
ependymoma -2.000 2.4e-10
glioblastoma -1.800 5.8e-05
group 3 medulloblastoma -1.400 1.1e-02
intraductal papillary-mucinous adenoma (... -2.100 2.2e-03
intraductal papillary-mucinous carcinoma... -2.300 2.0e-03
intraductal papillary-mucinous neoplasm ... -2.100 2.8e-02
lung carcinoma 2.700 1.1e-24
malignant mesothelioma -1.500 7.9e-05
medulloblastoma, large-cell -2.900 2.2e-05
oligodendroglioma -1.100 1.3e-07
ovarian cancer -4.700 2.1e-11
primitive neuroectodermal tumor -1.400 2.0e-02
psoriasis -1.600 1.4e-07
subependymal giant cell astrocytoma -1.405 2.3e-02
X-linked cerebral adrenoleukodystrophy -1.100 2.4e-02

Synonym

Accession Q99457 B2RCM0 O60788
Symbols MB20
NPL3

Gene

NAP1L3

PANTHER Protein Class (3)

  Ortholog (6)

Species Source Disease
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
OMA EggNOG
OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG

 UniProt Keyword (4)

 GO Component (1)

 GO Process (1)

 Compartment GO Term (11)

 HCA RNA Cell Line (41)

See all...

AA Sequence 

MAEADFKMVSEPVAHGVAEEEMASSTSDSGEESDSSSSSSSTSDSSSSSSTSGSSSGSGSSSSSSGSTSS      1 - 70
RSRLYRKKRVPEPSRRARRAPLGTNFVDRLPQAVRNRVQALRNIQDECDKVDTLFLKAIHDLERKYAELN     71 - 140
KPLYDRRFQIINAEYEPTEEECEWNSEDEEFSSDEEVQDNTPSEMPPLEGEEEENPKENPEVKAEEKEVP    141 - 210
KEIPEVKDEEKEVPKEIPEVKAEEKADSKDCMEATPEVKEDPKEVPQVKADDKEQPKATEAKARAAVRET    211 - 280
HKRVPEERLQDSVDLKRARKGKPKREDPKGIPDYWLIVLKNVDKLGPMIQKYDEPILKFLSDVSLKFSKP    281 - 350
GQPVSYTFEFHFLPNPYFRNEVLVKTYIIKAKPDHNDPFFSWGWEIEDCKGCKIDWRRGKDVTVTTTQSR    351 - 420
TTATGEIEIQPRVVPNASFFNFFSPPEIPMIGKLEPREDAILDEDFEIGQILHDNVILKSIYYYTGEVNG    421 - 490
TYYQFGKHYGNKKYRK                                                          491 - 506
//

Text Mined References (7)

PMID Year Title