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Tbio Unconventional myosin-Vc

May be involved in transferrin trafficking. Likely to power actin-based membrane trafficking in many physiologically crucial tissues.

 Comments

Property Summary

NCBI Gene PubMed Count 16
PubMed Score 11.20
PubTator Score 9.59

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (4)

Disease Target Count Z-score Confidence
Substance-Related Disorders 115 0.0 0.0
Disease Target Count Z-score Confidence
Carcinoma 11493 0.0 1.3
Endometrial cancer 311 0.0 0.5
Kidney cancer 2613 0.0 0.7
Disease Target Count Z-score Confidence
Griscelli syndrome 24 3.268 1.6

Expression

  Differential Expression (13)

Disease log2 FC p
ependymoma 1.800 1.1e-05
intraductal papillary-mucinous adenoma (... 1.500 2.3e-03
intraductal papillary-mucinous neoplasm ... 1.100 4.0e-02
lung carcinoma -2.300 1.8e-27
malignant mesothelioma -1.800 5.1e-06
non-small cell lung cancer -1.661 2.3e-13
osteosarcoma -1.435 2.2e-02
pancreatic cancer -1.100 3.9e-03
pancreatic ductal adenocarcinoma liver m... 1.428 2.8e-02
progressive supranuclear palsy -1.200 1.7e-02
psoriasis -1.100 1.4e-08
spina bifida -1.151 3.5e-02
tuberculosis -2.100 6.6e-08

Synonym

Accession Q9NQX4 Q6P1W8
Symbols

Gene

MYO5C

PANTHER Protein Class (3)

PDB

4L8T   4ZG4   5HMP  

  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG

 UniProt Keyword (15)

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 GO Function (4)

 GO Component (2)

 Compartment GO Term (20)

See all...

 GWAS Trait (1)

 HCA RNA Cell Line (53)

See all...

Pathway (1)

Gene RIF (12)

AA Sequence 

MAVAELYTQYNRVWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGEN      1 - 70
DLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGDMDPHIFAV     71 - 140
AEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAHVEDKVLASNPITEAVGNAKTT    141 - 210
RNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSA    211 - 280
EEFNYTRMGGNTVIEGVNDRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSE    281 - 350
DDSHLKVFCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQA    351 - 420
LQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPWTLIDFYDN    421 - 490
QPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPRMSNTSFVIQHFADKVEYKCE    491 - 560
GFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRS    561 - 630
SLYLLMETLNATTPHYVRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYG    631 - 700
ILMTKQELSFSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGW    701 - 770
LQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQAY    771 - 840
SRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVE    841 - 910
KLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQ    911 - 980
EKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGE    981 - 1050
HVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVR   1051 - 1120
SRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREE   1121 - 1190
NDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQ   1191 - 1260
RKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRV   1261 - 1330
IKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKLIQNLILDLKPRGVVVNMIPGLPAHIL   1331 - 1400
FMCVRYADSLNDANMLKSLMNSTINGIKQVVKEHLEDFEMLSFWLSNTCHFLNCLKQYSGEEEFMKHNSP   1401 - 1470
QQNKNCLNNFDLSEYRQILSDVAIRIYHQFIIIMEKNIQPIIVPGMLEYESLQGISGLKPTGFRKRSSSI   1471 - 1540
DDTDGYTMTSVLQQLSYFYTTMCQNGLDPELVRQAVKQLFFLIGAVTLNSLFLRKDMCSCRKGMQIRCNI   1541 - 1610
SYLEEWLKDKNLQNSLAKETLEPLSQAAWLLQVKKTTDSDAKEIYERCTSLSAVQIIKILNSYTPIDDFE   1611 - 1680
KRVTPSFVRKVQALLNSREDSSQLMLDTKYLFQVTFPFTPSPHALEMIQIPSSFKLGFLNRL           1681 - 1742
//

Text Mined References (18)

PMID Year Title