| Tbio | Myc target protein 1 |
May regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator. Does not seem to significantly affect growth cell capacity. Overexpression seems to mediate many of the known phenotypic features associated with MYC, including promotion of apoptosis, alteration of morphology, enhancement of anchorage-independent growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation (By similarity).
Comments
| Disease | Target Count | P-value |
|---|---|---|
| non-small cell lung cancer | 2890 | 6.1e-31 |
| lung adenocarcinoma | 2716 | 2.5e-15 |
| lung carcinoma | 2843 | 1.9e-10 |
| psoriasis | 6694 | 1.2e-08 |
| lung cancer | 4740 | 5.0e-06 |
| ductal carcinoma in situ | 1745 | 1.4e-04 |
| invasive ductal carcinoma | 2951 | 2.2e-04 |
| medulloblastoma, large-cell | 6241 | 1.2e-03 |
| interstitial cystitis | 2312 | 1.8e-03 |
| osteosarcoma | 7950 | 8.0e-03 |
| astrocytic glioma | 2597 | 4.1e-02 |
| acute myeloid leukemia | 783 | 4.7e-02 |
| Disease | log2 FC | p |
|---|---|---|
| acute myeloid leukemia | -4.200 | 4.7e-02 |
| astrocytic glioma | -1.200 | 4.1e-02 |
| ductal carcinoma in situ | -1.600 | 1.4e-04 |
| interstitial cystitis | 1.200 | 1.8e-03 |
| invasive ductal carcinoma | -2.300 | 2.2e-04 |
| lung adenocarcinoma | -1.900 | 2.5e-15 |
| lung cancer | -2.700 | 5.0e-06 |
| lung carcinoma | -1.700 | 1.9e-10 |
| medulloblastoma, large-cell | -1.100 | 1.2e-03 |
| non-small cell lung cancer | -2.338 | 6.1e-31 |
| osteosarcoma | -1.863 | 8.0e-03 |
| psoriasis | -1.100 | 1.2e-08 |
| Species | Source | Disease |
|---|---|---|
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| OMA EggNOG |
