Property Summary

NCBI Gene PubMed Count 10
PubMed Score 77.95

Knowledge Summary


No data available

Gene RIF (1)

23402768 Data suggest that humanin (the first small peptide of a putative set of mitochondrial derived peptides) exhibits strong cytoprotective actions against various stress and disease models.

AA Sequence

MATPGFSCLLLSTSEIDLPMKRRV                                                    1 - 24

Text Mined References (10)

PMID Year Title
25630734 2016 The human mitochondrial genome may code for more than 13 proteins.
23726511 2013 Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder.
23402768 2013 Humanin: a harbinger of mitochondrial-derived peptides?
20542501 2010 Immunolocalization of humanin in human sperm and testis.
19623253 2009 Humanin: a novel central regulator of peripheral insulin action.
19477263 2009 Evidence for potential functionality of nuclearly-encoded humanin isoforms.
15164054 2004 The DNA sequence and comparative analysis of human chromosome 10.
12732850 2003 Humanin peptide suppresses apoptosis by interfering with Bax activation.
12009529 2002 Evidence for in vivo production of Humanin peptide, a neuroprotective factor against Alzheimer's disease-related insults.
11371646 2001 A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta.