| Tdark | Mitochondrial fission regulator 2 |
May play a role in mitochondrial aerobic respiration essentially in the testis. Can also promote mitochondrial fission (By similarity).
Comments
| Disease | Target Count | P-value |
|---|---|---|
| breast carcinoma | 1638 | 5.1e-29 |
| non-small cell lung cancer | 2890 | 2.6e-15 |
| psoriasis | 6694 | 5.4e-13 |
| Breast cancer | 3578 | 3.2e-11 |
| glioblastoma | 5792 | 6.8e-08 |
| group 3 medulloblastoma | 4104 | 6.1e-07 |
| posterior fossa group A ependymoma | 468 | 9.5e-07 |
| atypical teratoid / rhabdoid tumor | 5112 | 2.0e-06 |
| medulloblastoma, large-cell | 6241 | 7.1e-06 |
| lung adenocarcinoma | 2716 | 3.0e-05 |
| adult high grade glioma | 3801 | 6.5e-05 |
| primitive neuroectodermal tumor | 3035 | 1.2e-04 |
| ovarian cancer | 8520 | 2.4e-04 |
| intraductal papillary-mucinous carcinoma (IPMC) | 2989 | 2.9e-04 |
| Atopic dermatitis | 952 | 4.3e-04 |
| adrenocortical carcinoma | 1428 | 5.6e-04 |
| invasive ductal carcinoma | 2951 | 1.0e-03 |
| osteosarcoma | 7950 | 1.8e-03 |
| intraductal papillary-mucinous neoplasm (IPMN) | 3291 | 2.0e-03 |
| ductal carcinoma in situ | 1745 | 2.4e-03 |
| Disease | log2 FC | p |
|---|---|---|
| adrenocortical carcinoma | 2.082 | 5.6e-04 |
| adult high grade glioma | 1.800 | 6.5e-05 |
| Atopic dermatitis | 1.200 | 4.3e-04 |
| atypical teratoid / rhabdoid tumor | 1.800 | 2.0e-06 |
| Breast cancer | 2.200 | 3.2e-11 |
| breast carcinoma | 1.100 | 5.1e-29 |
| ductal carcinoma in situ | 1.700 | 2.4e-03 |
| glioblastoma | 2.000 | 6.8e-08 |
| group 3 medulloblastoma | 2.800 | 6.1e-07 |
| intraductal papillary-mucinous carcinoma... | 2.200 | 2.9e-04 |
| intraductal papillary-mucinous neoplasm ... | 2.400 | 2.0e-03 |
| invasive ductal carcinoma | 1.900 | 1.0e-03 |
| lung adenocarcinoma | 1.100 | 3.0e-05 |
| medulloblastoma, large-cell | 2.100 | 7.1e-06 |
| non-small cell lung cancer | 1.831 | 2.6e-15 |
| osteosarcoma | -2.355 | 1.8e-03 |
| ovarian cancer | 1.700 | 2.4e-04 |
| posterior fossa group A ependymoma | 1.100 | 9.5e-07 |
| primitive neuroectodermal tumor | 2.200 | 1.2e-04 |
| psoriasis | 1.700 | 5.4e-13 |
MSLILNILREMLEYFGVPVEQVLLIWENKDYGSTRSIVRIIGKMLPLEPCRRPNFELIPLLNSVDSDNCG 1 - 70 SMVPSFADILYVANDEEASYLRFRNSIWKNEEEKVEIFHPLRLVRDPLSPAVRQKETVKNDLPVNEAAIR 71 - 140 KIAALENELTFLRSQIAAIVEMQELKNSTNSSSFGLSDERISLGQLSSSRAAHLSVDPDQLPGSVLSPPP 141 - 210 PPPLPPQFSSLQPPCFPPVQPGSNNICDSDNPATEMSKQNPAANKTNYSHHSKSQRNKDIPNMLDVLKDM 211 - 280 NKVKLRAIERSPGGRPIHKRKRQNSHWDPVSLISHALKQKFAFQEDDSFEKENRSWESSPFSSPETSRFG 281 - 350 HHISQSEGQRTKEEMVNTKAVDQGISNTSLLNSRI 351 - 385 //
