| Tbio | Metallothionein-1G |
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
Comments
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Esophageal Neoplasms | 69 | 0.0 | 0.0 |
| Disease | Target Count | P-value |
|---|---|---|
| non-small cell lung cancer | 2890 | 3.4e-12 |
| acute quadriplegic myopathy | 1158 | 8.3e-09 |
| ulcerative colitis | 1819 | 5.5e-08 |
| malignant mesothelioma | 3232 | 2.5e-07 |
| osteosarcoma | 7950 | 1.1e-06 |
| colon cancer | 1478 | 1.8e-05 |
| pancreatic cancer | 2398 | 2.4e-05 |
| group 3 medulloblastoma | 4104 | 5.7e-05 |
| lung adenocarcinoma | 2716 | 1.1e-04 |
| lung cancer | 4740 | 1.3e-04 |
| ovarian cancer | 8520 | 1.8e-04 |
| cystic fibrosis | 1696 | 2.9e-04 |
| medulloblastoma, large-cell | 6241 | 9.8e-04 |
| psoriasis | 6694 | 1.3e-03 |
| atypical teratoid / rhabdoid tumor | 5112 | 1.4e-03 |
| adrenocortical carcinoma | 1428 | 2.0e-03 |
| nephrosclerosis | 333 | 2.3e-03 |
| intraductal papillary-mucinous neoplasm (IPMN) | 3291 | 3.7e-03 |
| intraductal papillary-mucinous adenoma (IPMA) | 2955 | 9.5e-03 |
| primary pancreatic ductal adenocarcinoma | 1109 | 1.2e-02 |
| Endometriosis | 540 | 1.4e-02 |
| active Crohn's disease | 922 | 2.6e-02 |
| intraductal papillary-mucinous carcinoma (IPMC) | 2989 | 2.7e-02 |
| Disease | log2 FC | p |
|---|---|---|
| active Crohn's disease | -1.249 | 2.6e-02 |
| acute quadriplegic myopathy | 1.263 | 8.3e-09 |
| adrenocortical carcinoma | -1.186 | 2.0e-03 |
| atypical teratoid / rhabdoid tumor | -1.400 | 1.4e-03 |
| colon cancer | -2.100 | 1.8e-05 |
| cystic fibrosis | 1.128 | 2.9e-04 |
| Endometriosis | -2.839 | 1.4e-02 |
| group 3 medulloblastoma | -2.300 | 5.7e-05 |
| intraductal papillary-mucinous adenoma (... | -2.200 | 9.5e-03 |
| intraductal papillary-mucinous carcinoma... | -2.600 | 2.7e-02 |
| intraductal papillary-mucinous neoplasm ... | -3.800 | 3.7e-03 |
| lung adenocarcinoma | -1.300 | 1.1e-04 |
| lung cancer | -1.600 | 1.3e-04 |
| malignant mesothelioma | -1.700 | 2.5e-07 |
| medulloblastoma, large-cell | -2.000 | 9.8e-04 |
| nephrosclerosis | -1.130 | 2.3e-03 |
| non-small cell lung cancer | -1.741 | 3.4e-12 |
| osteosarcoma | 1.923 | 1.1e-06 |
| ovarian cancer | 1.800 | 1.8e-04 |
| pancreatic cancer | -1.500 | 2.4e-05 |
| primary pancreatic ductal adenocarcinoma | -2.075 | 1.2e-02 |
| psoriasis | -1.100 | 1.3e-03 |
| ulcerative colitis | -2.500 | 5.5e-08 |
