Tdark MS4A4E Putative membrane-spanning 4-domains subfamily A member 4E

Protein Summary

Description

Most MS4A genes, including MS4A4E, encode proteins with at least 4 potential transmembrane domains and N- and C-terminal cytoplasmic domains encoded by distinct exons.[supplied by OMIM, Apr 2004]

Uniprot Accession IDs

• Q96PG1
• Q3C1W1
• Q3C1W3
• Q3C1W4

Gene Name

• MS4A4E

Ensembl ID

• ENST00000398984
• ENSP00000381954
• ENSG00000214787
• ENST00000425663
• ENSP00000389556
• ENST00000526086
• ENSP00000435601
• ENST00000528394
• ENSP00000436446

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell line	0.49
disease	0.49
protein complex	0.41
cellular component	0.38
tissue sample	0.36

Protein Classes

PANTHER Classes

Protein / Receptor / Putative Membrane-spanning 4-domains Subfamily A Member 4e

DTO Classes

Protein / Receptor / Putative Membrane-spanning 4-domains Subfamily A Member 4e

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.11   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 11   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.11   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 11   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0