Protein Summary
May regulate the activity of kinases. The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- ENST00000319928
- ENSP00000315113
- ENSG00000142961
- ENST00000371940
- ENSP00000361008
- MOBKL2C
- MOB1E
- MOBKL2C
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor | 0.69 | ||
transcription factor binding site profile | 0.62 | ||
PubMedID | 0.59 | ||
tissue sample | 0.59 | ||
cell type or tissue | 0.57 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.59 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 80 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.59 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 80 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 1
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0