MMP28
Matrix metalloproteinase-28
Protein Summary
Can degrade casein. Could play a role in tissues homeostasis and repair. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. This gene encodes a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
- ENST00000605424
- ENSP00000473853
- ENSG00000271447
- ENST00000611911
- ENSP00000484430
- ENSG00000278843
- ENST00000612672
- ENSP00000483539
- ENST00000632360
- ENSP00000488096
- MMP25
- MM28
- MMP25
- MMP-25
- MMP-28
- EPILYSIN
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
protein domain | 0.99 | ||
cell type or tissue | 0.84 | ||
histone modification site profile | 0.69 | ||
tissue | 0.55 | ||
kinase perturbation | 0.54 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 87.48 (req: < 5)
Gene RIFs: 22 (req: <= 3)
Antibodies: 288 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 87.48 (req: >= 5)
Gene RIFs: 22 (req: > 3)
Antibodies: 288 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0