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Tbio
MIPEP
Mitochondrial intermediate peptidase

Protein Summary
Description
Cleaves proteins, imported into the mitochondrion, to their mature size. The product of this gene performs the final step in processing a specific class of nuclear-encoded proteins targeted to the mitochondrial matrix or inner membrane. This protein is primarily involved in the maturation of oxidative phosphorylation (OXPHOS)-related proteins. This gene may contribute to the functional effects of frataxin deficiency and the clinical manifestations of Friedreich ataxia. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000382172
  • ENSP00000371607
  • ENSG00000027001

Symbol
  • MIP
  • MIP
  • HMIP
  • COXPD31
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.88
transcription factor binding site profile
0.84
transcription factor perturbation
0.8
tissue sample
0.76
protein domain
0.58


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 90.73   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 346   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 90.73   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 346   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0