| Tbio | Microfibrillar-associated protein 3-like |
May participate in the nuclear signaling of EGFR and MAPK1/ERK2. May a have a role in metastasis.
Comments
| Disease | Target Count |
|---|---|
| Anxiety Disorders | 37 |
| Disease | Target Count | P-value |
|---|---|---|
| non-small cell lung cancer | 2798 | 5.1e-11 |
| sonic hedgehog group medulloblastoma | 1482 | 2.7e-07 |
| lung adenocarcinoma | 2714 | 8.2e-07 |
| malignant mesothelioma | 3163 | 1.2e-06 |
| interstitial cystitis | 2299 | 4.8e-06 |
| medulloblastoma, large-cell | 6234 | 5.1e-06 |
| atypical teratoid/rhabdoid tumor | 1095 | 3.6e-05 |
| pituitary cancer | 1972 | 3.9e-05 |
| psoriasis | 6685 | 5.8e-05 |
| lung cancer | 4473 | 7.9e-05 |
| osteosarcoma | 7933 | 8.8e-05 |
| Breast cancer | 3098 | 1.9e-04 |
| ovarian cancer | 8491 | 1.7e-03 |
| primitive neuroectodermal tumor | 3031 | 2.4e-03 |
| hepatocellular carcinoma | 550 | 3.3e-03 |
| pancreatic carcinoma | 567 | 3.7e-03 |
| pancreatic cancer | 2300 | 3.7e-03 |
| Down syndrome | 548 | 4.6e-03 |
| gastric cancer | 436 | 9.0e-03 |
| pancreatic ductal adenocarcinoma liver metastasis | 1795 | 1.0e-02 |
| Waldenstrons macroglobulinemia | 764 | 2.6e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Globe disease | 57 | 0.0 | 1.0 |
| Disease | log2 FC | p |
|---|---|---|
| gastric cancer | 1.600 | 9.0e-03 |
| hepatocellular carcinoma | 1.400 | 3.3e-03 |
| pancreatic cancer | 1.900 | 3.7e-03 |
| Waldenstrons macroglobulinemia | -1.039 | 2.6e-02 |
| malignant mesothelioma | 1.800 | 1.2e-06 |
| psoriasis | -2.100 | 5.8e-05 |
| osteosarcoma | -2.051 | 8.8e-05 |
| sonic hedgehog group medulloblastoma | -4.300 | 2.7e-07 |
| atypical teratoid/rhabdoid tumor | -2.100 | 3.6e-05 |
| medulloblastoma, large-cell | -4.100 | 5.1e-06 |
| primitive neuroectodermal tumor | -2.900 | 2.4e-03 |
| pancreatic ductal adenocarcinoma liver m... | -2.033 | 1.0e-02 |
| non-small cell lung cancer | -1.481 | 5.1e-11 |
| lung cancer | -2.100 | 7.9e-05 |
| interstitial cystitis | -4.100 | 4.8e-06 |
| lung adenocarcinoma | -1.270 | 8.2e-07 |
| pancreatic carcinoma | 1.900 | 3.7e-03 |
| Breast cancer | -1.700 | 1.9e-04 |
| ovarian cancer | 2.000 | 1.7e-03 |
| pituitary cancer | -3.000 | 3.9e-05 |
| Down syndrome | 1.100 | 4.6e-03 |
| PMID | Text | |
|---|---|---|
| 24735981 | MFAP3L activation promotes colorectal cancer cell invasion and metastasis. |
MDRLKSHLTVCFLPSVPFLILVSTLATAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSV 1 - 70 YGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTL 71 - 140 RVIFTSGDMGVYYMVVCLVAFTIVMVLNITRLCMMSSHLKKTEKAINEFFRTEGAEKLQKAFEIAKRIPI 141 - 210 ITSAKTLELAKVTQFKTMEFARYIEELARSVPLPPLIMNCRTIMEEIMEVVGLEEQGQNFVRHTPEGQEA 211 - 280 ADRDEVYTIPNSLKRSDSPAADSDASSLHEQPQQIAIKVSVHPQSKKEHADDQEGGQFEVKDVEETELSA 281 - 350 EHSPETAEPSTDVTSTELTSEEPTPVEVPDKVLPPAYLEATEPAVTHDKNTCIIYESHV 351 - 409 //
| PMID | Year | Title | |
|---|---|---|---|
| 25390645 | 2014 | Genome-wide and gene-based association studies of anxiety disorders in European and African American samples. | |
| 24735981 | 2014 | MFAP3L activation promotes colorectal cancer cell invasion and metastasis. | |
| 15815621 | 2005 | Generation and annotation of the DNA sequences of human chromosomes 2 and 4. | |
| 15489334 | 2004 | The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). | |
| 14702039 | 2004 | Complete sequencing and characterization of 21,243 full-length human cDNAs. | |
| 12477932 | 2002 | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. | |
| 9734811 | 1998 | Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. |
