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Tdark
METTL2A
Methyltransferase-like protein 2A

Protein Summary
Description
Probable S-adenosyl-L-methionine-dependent methyltransferase that mediates 3-methylcytidine modification of some tRNAs.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000311506
  • ENSP00000309610
  • ENSG00000087995

Symbol
  • METTL2
  • METTL2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.89
cellular component
0.84
transcription factor binding site profile
0.8
transcription factor perturbation
0.68
tissue
0.63


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.98   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 116   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.98   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 116   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0