Tbio MAST3 Microtubule-associated serine/threonine-protein kinase 3

Protein Summary

Uniprot Accession IDs

• O60307
• Q7LDZ8
• Q9UPI0

Gene Name

• MAST3

Ensembl ID

• ENST00000262811
• ENSP00000262811
• ENSG00000099308

Symbol

• KIAA0561

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.97
molecular function	0.95
disease perturbation	0.79
gene perturbation	0.68
small molecule perturbation	0.6

Protein Classes

PANTHER Classes

Protein / Transferase / Kinase / Protein Kinase / Non-receptor Serine/threonine Protein Kinase / Microtubule-associated Serine/threonine-protein Kinase 3

Protein / Transfer/carrier Protein / Microtubule-associated Serine/threonine-protein Kinase 3

Protein / Calcium-binding Protein / Intracellular Calcium-sensing Protein / Calmodulin / Microtubule-associated Serine/threonine-protein Kinase 3

Protein / Calcium-binding Protein / Annexin / Microtubule-associated Serine/threonine-protein Kinase 3

DTO Classes

Protein / Kinase / Protein Kinase / Agc Group / Mast Family / Microtubule-associated Serine/threonine-protein Kinase 3

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.25   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 153   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.25   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 153   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 1

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0