Property Summary

NCBI Gene PubMed Count 14
PubMed Score 5.03
PubTator Score 9.53

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (12)

Disease log2 FC p
astrocytic glioma 1.500 8.6e-03
atypical teratoid / rhabdoid tumor 1.400 4.0e-04
non-small cell lung cancer 1.227 3.5e-17
intraductal papillary-mucinous carcinoma... 1.300 2.4e-02
fibroadenoma 1.900 1.8e-02
interstitial cystitis -1.600 1.8e-04
posterior fossa group B ependymoma 1.400 5.9e-06
spina bifida -2.084 4.7e-02
ductal carcinoma in situ 1.100 2.2e-02
invasive ductal carcinoma 1.100 3.1e-02
ulcerative colitis -1.600 3.4e-06
ovarian cancer -1.600 1.3e-04

Gene RIF (4)

PMID Text
24567356 MarvelD3 couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival.
21763689 MarvelD3 is transcriptionally downregulated in Snail-induced epithelial-mesenchymal transition during the progression for the pancreatic cancer.
20164257 marvelD3, occludin, and tricellulin define the tight junction-associated MARVEL protein family
20028514 MarvelD3 co-localises with occludin at tight junctions in intestinal and corneal epithelial cells.

AA Sequence

MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD      1 - 70
RNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDAAAPPGPAPWEAPEP     71 - 140
PQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQSEAEGLLECHKCKYLCTGRACCQMLEVLLNL    141 - 210
LILACSSVSYSSTGGYTGITSLGGIYYYQFGGAYSGFDGADGEKAQQLDVQFYQLKLPMVTVAMACSGAL    211 - 280
TALCCLFVAMGVLRVPWHCPLLLVTEGLLDMLIAGGYIPALYFYFHYLSAAYGSPVCKERQALYQSKGYS    281 - 350
GFGCSFHGADIGAGIFAALGIVVFALGAVLAIKGYRKVRKLKEKPAEMFEF                       351 - 401
//

Text Mined References (14)

PMID Year Title
24567356 2014 MarvelD3 couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival.
23203797 2013 In tight junctions, claudins regulate the interactions between occludin, tricellulin and marvelD3, which, inversely, modulate claudin oligomerization.
22895189 2012 Genome-wide association study indicates two novel resistance loci for severe malaria.
21763689 2011 Downregulation of tight junction-associated MARVEL protein marvelD3 during epithelial-mesenchymal transition in human pancreatic cancer cells.
20164257 2010 Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions.
20028514 2009 Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family.
17207965 2007 hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.
16341674 2005 Transcriptome analysis of human gastric cancer.
15616553 2004 The sequence and analysis of duplication-rich human chromosome 16.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15342556 2004 Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.
15146197 2004 Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.