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Tbio
MAP1S
Microtubule-associated protein 1S

Protein Summary
Description
Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000324096
  • ENSP00000325313
  • ENSG00000130479
  • ENST00000544059
  • ENSP00000439243

Symbol
  • BPY2IP1
  • C19orf5
  • MAP8
  • VCY2IP1
  • MAP8
  • BPY2IP1
  • C19orf5
  • VCY2IP1
  • VCY2IP-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.98
cellular component
0.88
kinase
0.79
hub protein
0.75
molecular function
0.73


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 53.18   (req: < 5)
Gene RIFs: 16   (req: <= 3)
Antibodies: 178   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 53.18   (req: >= 5)
Gene RIFs: 16   (req: > 3)
Antibodies: 178   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 19
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0