Tdark MAGEE2 Melanoma-associated antigen E2

Protein Summary

Description

This gene encodes a member of the E subfamily of MAGE (melanoma antigen-encoding gene) gene family. The gene is intronless and the encoded protein has two of the MAGE domains which are characteristic of MAGE family proteins. [provided by RefSeq, Sep 2011]

Uniprot Accession IDs

• Q8TD90
• Q5JSI5

Gene Name

• MAGEE2

Ensembl ID

• ENST00000373359
• ENSP00000362457
• ENSG00000186675

Symbol

• HCA3
• HCA3

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
interacting protein	0.73
cell line	0.5
tissue	0.5
PubMedID	0.44
virus perturbation	0.41

Protein Classes

PANTHER Classes

Protein / Cell Adhesion Molecule / Melanoma-associated Antigen E2

DTO Classes

Protein / Cell Adhesion / Melanoma-associated Antigen E2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.87   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 73   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.87   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 73   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0