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Tbio Ly6/PLAUR domain-containing protein 4


 Comments

Property Summary

NCBI Gene PubMed Count 4
PubMed Score 167.99
PubTator Score 570.03

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (2)

Disease Target Count P-value
diabetes mellitus 1663 1.3e-03
Disease Target Count Z-score Confidence
Mitral valve insufficiency 17 4.05 2.0
Listeriosis 17 3.216 1.6

Expression

  Differential Expression (1)

Disease log2 FC p
diabetes mellitus 1.200 1.3e-03

Synonym

Accession Q6UWN0 Q8IYW0
Symbols SMR

Gene

LYPD4

  Ortholog (1)

Species Source Disease
Macaque OMA Inparanoid

 UniProt Keyword (11)

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 GO Component (2)

 Compartment GO Term (13)

 HCA RNA Cell Line (30)

See all...

Pathway (4)

Protein-protein Interaction (67)

ELP6   POLE   SMG8   TOR3A   WRAP53   LRWD1   GALNS   GREB1L   PANK4   BRIP1   TUBA4A   VPS13B   VPS16   NPTX1   NPTX2   ERN1   PRR14   FBN2   BORA   FAM69A   ECD   GALNT12   LETM1   FBXL18   OBSCN   SEC23IP   ADAMTS2   APAF1   POGLUT1   CBWD3   DPYSL4   NPRL3   CTR9   AP3M2   STIL   NBR1   FUT11   USP34   PRMT6   EDEM2   ESPL1   ASPHD2   KIF18A   GDF11   ADCK1   NAGLU   N4BP2L2   TRMT44   LSS   OAF   ME1   TDP2   TSPAN6   PCSK5   GNPAT   VPS18   XYLT2   AP5Z1   DENND4A   PPT2   TROAP   KIF1A   JMJD4   LRFN3   FAM198A   LMLN   MICA  

Gene RIF (1)

PMID Text
18187620 Knockdown of LY6/PLAUR domain containing 4 (LYPD4) by siRNA inhibits HIV-1 replication in HeLa-derived TZM-bl cells

AA Sequence 

MGPQHLRLVQLFCLLGAISTLPRAGALLCYEATASRFRAVAFHNWKWLLMRNMVCKLQEGCEETLVFIET      1 - 70
GTARGVVGFKGCSSSSSYPAQISYLVSPPGVSIASYSRVCRSYLCNNLTNLEPFVKLKASTPKSITSASC     71 - 140
SCPTCVGEHMKDCLPNFVTTNSCPLAASTCYSSTLKFQAGFLNTTFLLMGCAREHNQLLADFHHIGSIKV    141 - 210
TEVLNILEKSQIVGAASSRQDPAWGVVLGLLFAFRD                                      211 - 246
//

Text Mined References (4)

PMID Year Title
16751776 2006 A germline-specific class of small RNAs binds mammalian Piwi proteins.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
12975309 2003 The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.