Tbio LYG2 Lysozyme g-like protein 2

Protein Summary

Description

May act as a potent antibacterial protein that may play a role in the innate immunity. The protein encoded by this gene contains a SLT domain, a protein domain present in bacterial lytic transglycosylase (SLT) and in eukaryotic lysozymes (GEWL). SLT domain catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyglucosamine (GlcNAc). [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q86SG7
• Q496G2
• Q53RW0

Gene Name

• LYG2

Ensembl ID

• ENST00000333017
• ENSP00000327533
• ENSG00000185674
• ENST00000409238
• ENSP00000386939
• ENST00000423800
• ENSP00000390357
• ENST00000626374
• ENSP00000487012

Symbol

• LYGH
• LYGH
• LYSG2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.68
cell type or tissue	0.54
tissue	0.45
protein domain	0.41
transcription factor	0.39

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.75   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 58   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.75   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 58   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0