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Tbio
LY86
Lymphocyte antigen 86

Protein Summary
Description
May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000230568
  • ENSP00000230568
  • ENSG00000112799
  • ENST00000379953
  • ENSP00000369286

Symbol
  • MD1
  • MD1
  • MD-1
  • MMD-1
  • dJ80N2.1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.92
tissue sample
0.7
transcription factor perturbation
0.68
kinase perturbation
0.66
disease perturbation
0.62


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 462.57   (req: < 5)
Gene RIFs: 13   (req: <= 3)
Antibodies: 341   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 462.57   (req: >= 5)
Gene RIFs: 13   (req: > 3)
Antibodies: 341   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0