Property Summary

NCBI Gene PubMed Count 8
PubMed Score 10.60
PubTator Score 0.31

Knowledge Summary


No data available


  Disease (1)

Disease Target Count P-value
periodontitis 269 3.3e-16
psoriasis 6685 7.8e-04
diabetes mellitus 1663 1.8e-03
Atopic dermatitis 944 4.0e-03
esophageal adenocarcinoma 737 2.7e-02


  Differential Expression (5)

Disease log2 FC p
esophageal adenocarcinoma -1.900 2.7e-02
psoriasis -1.500 7.8e-04
periodontitis -1.100 3.3e-16
Atopic dermatitis -1.400 4.0e-03
diabetes mellitus 1.400 1.8e-03

Gene RIF (3)

20628086 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19913121 Observational study of gene-disease association. (HuGE Navigator)
19851445 Observational study of gene-disease association. (HuGE Navigator)

AA Sequence


Text Mined References (11)

PMID Year Title
20628086 2010 Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
19913121 2009 Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
19851445 2009 High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.
17008713 2006 Characterization of the five novel Ly-6 superfamily members encoded in the MHC, and detection of cells expressing their potential ligands.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14656967 2003 Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.
14574404 2003 The DNA sequence and analysis of human chromosome 6.
12975309 2003 The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
12079290 2002 Transcriptional analysis of a novel cluster of LY-6 family members in the human and mouse major histocompatibility complex: five genes with many splice forms.
10384126 1999 Genes encoding three new members of the leukocyte antigen 6 superfamily and a novel member of Ig superfamily, together with genes encoding the regulatory nuclear chloride ion channel protein (hRNCC) and an N omega-N omega-dimethylarginine dimethylaminohydrolase homologue, are found in a 30-kb segment of the MHC class III region.