You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
LRRC39
Leucine-rich repeat-containing protein 39

Protein Summary
Description
Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress. May regulate expression of other M-band proteins via an SRF-dependent pathway. Important for normal contractile function in heart.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000342895
  • ENSP00000344470
  • ENSG00000122477
  • ENST00000370137
  • ENSP00000359156
  • ENST00000370138
  • ENSP00000359157
  • ENST00000620882
  • ENSP00000480740
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.68
tissue
0.62
cell type or tissue
0.58
tissue sample
0.5
cell line
0.48


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.53   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 164   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.53   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 164   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0