Leucine-rich repeat-containing protein 23

Property Summary

NCBI Gene PubMed Count	10
PubMed Score	0.28

PubTator Score	0.20

Knowledge Summary

Patent

No data available

TINX Plot

Disease (2)

Expression Atlas
JensenLab Text Mining

Disease	Target Count	P-value
ependymoma	4679	3.5e-09
nasopharyngeal carcinoma	1058	1.7e-07

Disease	Target Count	Z-score	Confidence
Ciliopathy	71	4.488	2.2

Expression

Specificity
Differential

Differential Expression (2)

Disease	log2 FC	p
ependymoma	1.800	3.5e-09
nasopharyngeal carcinoma	-1.200	1.7e-07

Testis 18,518

Brain - Cerebellar Hemisphere 18,015

Brain - Cerebellum 17,983

Pituitary 18,147

Ovary 17,971

Uterus 17,618

Brain - Spinal cord (cervical c-1) 17,973

Thyroid 18,024

Brain - Hypothalamus 18,169

Nerve - Tibial 18,007

Brain - Frontal Cortex (BA9) 18,069

Brain - Nucleus accumbens (basal ganglia... 18,024

Brain - Substantia nigra 17,981

Brain - Caudate (basal ganglia) 18,001

Brain - Cortex 18,039

Brain - Anterior cingulate cortex (BA24) 17,989

Brain - Amygdala 18,006

Artery - Aorta 17,896

Artery - Coronary 17,949

Brain - Hippocampus 18,011

Colon - Sigmoid 18,089

Prostate 18,213

Brain - Putamen (basal ganglia) 17,863

Vagina 17,834

Lung 18,057

Esophagus - Muscularis 18,017

Esophagus - Gastroesophageal Junction 18,000

Cells - Transformed fibroblasts 17,577

Cells - EBV-transformed lymphocytes 18,186

Adipose - Visceral (Omentum) 17,937

Stomach 17,879

Kidney - Cortex 17,329

Artery - Tibial 17,631

Heart - Atrial Appendage 17,896

Skin - Not Sun Exposed (Suprapubic) 18,081

Breast - Mammary Tissue 18,103

Adrenal Gland 18,071

Adipose - Subcutaneous 18,110

Skin - Sun Exposed (Lower leg) 17,968

Muscle - Skeletal 17,778

Spleen 17,614

Small Intestine - Terminal Ileum 17,954

Minor Salivary Gland 18,005

Esophagus - Mucosa 18,076

Heart - Left Ventricle 18,006

Colon - Transverse 17,825

Whole Blood 17,439

Pancreas 18,123

Liver 18,071

Adult Testis 10,836

Fetal Ovary 9,118

Platelets 6,131

Blood platelet

Ovary

Testis

adipose tissue 15,837

adrenal gland 15,963

appendix 16,247

bone marrow 14,571

breast 16,063

cerebral cortex 16,630

cervix, uterine 15,871

colon 15,959

duodenum 15,975

endometrium 16,349

epididymis 15,863

esophagus 15,898

fallopian tube 16,245

gallbladder 16,333

heart muscle 14,972

kidney 15,917

liver 14,587

lung 16,312

lymph node 15,833

ovary 15,408

pancreas 14,070

parathyroid gland 14,769

placenta 15,937

prostate 16,460

rectum 15,705

salivary gland 14,981

seminal vesicle 15,918

skeletal muscle 14,011

skin 16,206

small intestine 16,154

smooth muscle 15,857

spleen 15,972

stomach 16,099

testis 17,936

thyroid gland 15,959

tonsil 15,400

urinary bladder 15,814

Liver and Pancreas 16,750

Digestive Tract 17,369

Urinary Tract 16,678

Endocrine System 18,159

Blood and immune system 16,909

Respiratory system 16,393

Female tissues 17,400

Male tissues 17,142

Skin and soft tissues 17,230

Nervous System 16,725

Cardiovascular System 15,192

See source...

Auditory vesicle 24

Flagellate 17

See source...

Synonym

Accession	Q53EV4 A8K8C6 D3DUT1 Q8N6K6 Q92977 Q99620
Symbols	LRPB7

Gene

LRRC23

Ortholog (9)

Species	Source	Disease
Macaque 12,761	Inparanoid OMA
Rat 15,117	Inparanoid OMA
Mouse 16,570	Inparanoid OMA
Horse 14,252	Inparanoid OMA
Dog 15,073	Inparanoid OMA
Opossum 12,230	Inparanoid OMA
Cow 15,320	Inparanoid OMA
Zebrafish 9,726	Inparanoid OMA
Xenopus 10,468	Inparanoid OMA

UniProt Keyword (7)

Complete proteome 20,231

Polymorphism 12,194

Reference proteome 20,231

Repeat 4,916

Alternative splicing 10,528

Leucine-rich repeat 312

Coiled coil 2,153

Compartment GO Term (6)

Cell 16,178

Cell part 16,177

Nucleoli 942

Radial spoke 23

Radial spoke head 14

cellular_component 18,320

IMPC Phenotype (1)

decreased circulating serum albumin leve... 82

MGI Phenotype (1)

reproductive system phenotype 1,999

HCA RNA Cell Line (56)

A-431 16,131

A549 15,174

AF22 16,160

AN3-CA 15,648

ASC TERT1 14,842

BEWO 16,726

BJ 15,448

BJ hTERT+ 15,353

BJ hTERT+ SV40 Large T+ 15,609

BJ hTERT+ SV40 Large T+ RasG12V 15,493

See all...

AA Sequence

MSDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMKEGLSLLCKTGNGLAHA      1 - 70
YVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKADGNRLRSAQMNELPYLQIAS     71 - 140
FAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGINLPKLKNLYLAQN    141 - 210
MLKKVEGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALVLLDN    211 - 280
PCTDETSYRQEALVQMPYLERLDKEFYEEEERAEADVIRQRLKEEKEQEPEPQRDLEPEQSLI           281 - 343
//

Text Mined References (11)

Summary
Details

	PMID	Year	Title