| Tbio | Myogenesis-regulating glycosidase |
Putative glycosidase. Promotes myogenesis by activating AKT signaling through the maturation and secretion of IGF2.
Comments
| Disease | Target Count | P-value |
|---|---|---|
| ovarian cancer | 8520 | 4.1e-07 |
| Duchenne muscular dystrophy | 601 | 1.1e-06 |
| acute quadriplegic myopathy | 1158 | 1.8e-05 |
| medulloblastoma, large-cell | 6241 | 2.1e-05 |
| Astrocytoma, Pilocytic | 3081 | 2.7e-05 |
| group 3 medulloblastoma | 4104 | 5.6e-05 |
| glioblastoma | 5792 | 7.4e-04 |
| atypical teratoid / rhabdoid tumor | 5112 | 1.9e-03 |
| ulcerative colitis | 1819 | 4.2e-03 |
| osteosarcoma | 7950 | 5.7e-03 |
| pancreatic ductal adenocarcinoma liver metastasis | 1962 | 6.1e-03 |
| Disease | log2 FC | p |
|---|---|---|
| acute quadriplegic myopathy | -1.371 | 1.8e-05 |
| Astrocytoma, Pilocytic | -1.500 | 2.7e-05 |
| atypical teratoid / rhabdoid tumor | -1.100 | 1.9e-03 |
| Duchenne muscular dystrophy | -1.209 | 1.1e-06 |
| glioblastoma | -1.100 | 7.4e-04 |
| group 3 medulloblastoma | -2.300 | 5.6e-05 |
| medulloblastoma, large-cell | -1.800 | 2.1e-05 |
| osteosarcoma | 1.154 | 5.7e-03 |
| ovarian cancer | 1.800 | 4.1e-07 |
| pancreatic ductal adenocarcinoma liver m... | -1.070 | 6.1e-03 |
| ulcerative colitis | -1.200 | 4.2e-03 |
MLQNPQEKSQAYPRRRRPGCYAYRQNPEAIAAAAMYTFLPDNFSPAKPKPSKDLKPLLGSAVLGLLLVLA 1 - 70 AVVAWCYYSVSLRKAERLRAELLDLKAGGFSIRNQKGEQVFRLAFRSGALDLDSCSRDGALLGCSLTADG 71 - 140 LPLHFFIQTVRPKDTVMCYRVRWEEAAPGRAVEHAMFLGDAAAHWYGGAEMRTQHWPIRLDGQQEPQPFV 141 - 210 TSDVYSSDAAFGGILERYWLSSRAAAIKVNDSVPFHLGWNSTERSLRLQARYHDTPYKPPAGRAAAPELS 211 - 280 YRVCVGSDVTSIHKYMVRRYFNKPSRVPAPEAFRDPIWSTWALYGRAVDQDKVLRFAQQIRLHHFNSSHL 281 - 350 EIDDMYTPAYGDFDFDEVKFPNASDMFRRLRDAGFRVTLWVHPFVNYNSSRFGEGVERELFVREPTGRLP 351 - 420 ALVRWWNGIGAVLDFTHPKARDWFQGHLRRLRSRYSVASFKFDAGEVSYLPRDFSTYRPLPDPSVWSRRY 421 - 490 TEMALPFFSLAEVRVGYQSQNISCFFRLVDRDSVWGYDLGLRSLIPAVLTVSMLGYPFILPDMVGGNAVP 491 - 560 QRTAGGDVPERELYIRWLEVAAFMPAMQFSIPPWRYDAEVVAIAQKFAALRASLVAPLLLELAGEVTDTG 561 - 630 DPIVRPLWWIAPGDETAHRIDSQFLIGDTLLVAPVLEPGKQERDVYLPAGKWRSYKGELFDKTPVLLTDY 631 - 700 PVDLDEIAYFTWAS 701 - 714 //
