Property Summary

NCBI Gene PubMed Count 9
PubMed Score 22.13
PubTator Score 6.34

Knowledge Summary


No data available


  Differential Expression (10)

Disease log2 FC p
Multiple myeloma 1.229 2.5e-03
astrocytic glioma -1.200 3.6e-02
ependymoma -1.600 4.4e-02
osteosarcoma -1.673 2.3e-05
primary pancreatic ductal adenocarcinoma -1.017 5.1e-03
lung cancer 1.100 8.3e-04
adult high grade glioma -1.100 8.7e-05
subependymal giant cell astrocytoma -1.634 3.8e-02
ovarian cancer 2.100 1.1e-04
pancreatic cancer -1.100 3.4e-03

Gene RIF (4)

25582440 Results showed KCMF1 C-terminus binds directly to RAD6, whereas N-terminal domains interact with UBR4 and point mutations found in X-linked intellectual disability (XLID) patients specifically lose the interaction with KCMF1 and UBR4.
24980667 Data indicate that expressions of miR-210 and potassium channel modulatory factor 1 (KCMF1) exhibited an inverse correlation in placentas from patients with severe preeclampsia.
16314831 Suppression of KCMF1 by constitutive high CD99 expression levels contribute to the malignant properties of Ewing's sarcoma by promoting growth and migration of tumor cells
15581609 Data indicate that FIGC upregulation in response to basic fibroblast growth factor in gastric cancer might be implicated in carcinogenesis through dysregulation of growth modulator.

AA Sequence

GCVDIMPLDVALENLNLKESNKGNEPPPPPL                                           351 - 381

Text Mined References (17)

PMID Year Title
25582440 2015 KCMF1 (potassium channel modulatory factor 1) Links RAD6 to UBR4 (ubiquitin N-recognin domain-containing E3 ligase 4) and lysosome-mediated degradation.
24980667 2014 MicroRNA-210 contributes to preeclampsia by downregulating potassium channel modulatory factor 1.
24275569 2014 An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
23186163 2013 Toward a comprehensive characterization of a human cancer cell phosphoproteome.
21269460 2011 Initial characterization of the human central proteome.
20068231 2010 Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
18691976 2008 Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
18669648 2008 A quantitative atlas of mitotic phosphorylation.
17974005 2007 The full-ORF clone resource of the German cDNA Consortium.
16314831 2006 Suppression of KCMF1 by constitutive high CD99 expression is involved in the migratory ability of Ewing's sarcoma cells.
15581609 2004 FIGC, a novel FGF-induced ubiquitin-protein ligase in gastric cancers.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12810064 2003 Debt91, a putative zinc finger protein differentially expressed during epithelial morphogenesis.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
9110174 1997 Large-scale concatenation cDNA sequencing.
8619474 1996 A "double adaptor" method for improved shotgun library construction.