Tbio JAKMIP1 Janus kinase and microtubule-interacting protein 1

Protein Summary

Description

Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.

Uniprot Accession IDs

• Q96N16
• A6H2J2
• A6H2J3
• A6H2J4
• A6H2J5
• A8MTK6
• B4DHZ8
• B8ZZR7
• D3DVT0
• Q86Y69
• Q8N7G3

Gene Name

• JAKMIP1

Ensembl ID

• ENST00000282924
• ENSP00000282924
• ENSG00000152969
• ENST00000409021
• ENSP00000386711
• ENST00000409371
• ENSP00000387042
• ENST00000409831
• ENSP00000386925
• ENST00000410077
• ENSP00000386745

Symbol

• GABABRBP
• JAMIP1
• MARLIN1
• JAMIP1
• MARLIN1
• Gababrbp

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
trait	0.97
cell type or tissue	0.68
tissue	0.63
phenotype	0.61
PubMedID	0.61

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.74   (req: < 5)

Gene RIFs: 7   (req: <= 3)

Antibodies: 161   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.74   (req: >= 5)

Gene RIFs: 7   (req: > 3)

Antibodies: 161   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 12

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0