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Tdark IQ and ubiquitin-like domain-containing protein

May play roles in cilia formation and/or maintenance.

 Comments

Property Summary

NCBI Gene PubMed Count 7
PubMed Score 7.06
PubTator Score 0.25

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (2)

Disease Target Count P-value
ependymoma 4679 3.4e-10
non-small cell lung carcinoma 317 6.1e-09
lung adenocarcinoma 2716 6.7e-09
nasopharyngeal carcinoma 1058 3.6e-07
Disease Target Count Z-score Confidence
Carcinoma 11493 0.0 1.1
Kidney cancer 2613 0.0 0.5

Expression

  Differential Expression (4)

Disease log2 FC p
ependymoma 2.300 3.4e-10
lung adenocarcinoma -1.500 6.7e-09
nasopharyngeal carcinoma -1.400 3.6e-07
non-small cell lung carcinoma -1.200 6.1e-09

Synonym

Accession Q8NA54 A4D0X0 Q49AL6 Q4G189 Q5BJD9 Q6NUH6 Q8N9Y2
Symbols

Gene

IQUB

PDB

2DAF  

  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG

 UniProt Keyword (6)

 GO Component (2)

 GO Process (2)

 Compartment GO Term (3)

 IMPC Phenotype (1)

 MGI Phenotype (1)

 GWAS Trait (1)

 HCA RNA Cell Line (41)

See all...

Protein-protein Interaction (2)

TLR6   BTBD1  

Gene RIF (2)

AA Sequence 

MSNQQEKYEAQNIVNSTEESDDAFDTVTIPVPSEEPQESDQTEEHESGIEQFSESHAIHVEEQSDQSFSS      1 - 70
LEPDNEQLMEEVISPRQVSYTPQHHEKQYAMQRPNDDSLAFLDKIKSVKESLQESVEDSLATVKVVLIPV     71 - 140
GQEIVIPFKVDTILKYLKDHFSHLLGIPHSVLQIRYSGKILKNNETLVQHGVKPQEIVQVEIFSTNPDLY    141 - 210
PVRRIDGLTDVSQIITVTVQTGLDQYQQVPVEIVKSDFHKPFLGGFRHKVTGVEYHNAGTQTVPKRIPER    211 - 280
LSIFCRDTQTVFQKKNLQQTTNTTSTQMTNIGVYVSNMTDKLVTPGKYFSAAEYHAQRLKAVIVIQTYYR    281 - 350
QWHAKIFVENLRRQKSLRLEWETQQELRKIREKEEWIKLDYHRRHNPKTNEDFEFLYNALEFWRQEELTR    351 - 420
INQSFTGAERKAALCELLEKETQIIASIGRHRYIAYMANQEAAIQAFLDKCSAPKIWRTPNGKTIEMDTQ    421 - 490
FTIRARELQNIYKCIMLKNISQDERLDVLLTLKHTVKEHECKLTQEILELIDREVDLMMRGVKHHNLEGL    491 - 560
RKRIATLFFHYIKTPLFNPEVAKYLKVPQDPLKFYKKIYFCHSCQLYLPSTEFSVSSTSRRIYRCRNCIN    561 - 630
LQNEAQKRESFLKYKCLLQQLYYTEADYEDDSKIAFLMQLQDIQYLTENIWASQSVLSACDNLSDLVMVR    631 - 700
WNKSLEWSPWNCILLTKDEAAAHLKLTSIEEGYERSFIHKIKHKHILAKNYFSQVPVLASFILDDGEIDE    701 - 770
IRWKYHSDTTPKIIESQRPPH                                                     771 - 791
//

Text Mined References (9)

PMID Year Title