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Tbio
IL13RA2
Interleukin-13 receptor subunit alpha-2

Protein Summary
Description
Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4). The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000243213
  • ENSP00000243213
  • ENSG00000123496
  • ENST00000371936
  • ENSP00000361004

Symbol
  • IL13R
  • CT19
  • IL-13R
  • IL13BP
  • CD213A2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
1
tissue
0.71
tissue sample
0.66
biological term
0.65
protein domain
0.58


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 35.02   (req: < 5)
Gene RIFs: 84   (req: <= 3)
Antibodies: 507   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 35.02   (req: >= 5)
Gene RIFs: 84   (req: > 3)
Antibodies: 507   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0