IKZF5
Zinc finger protein Pegasus
Protein Summary
DNA-binding protein that binds to the 5'GNNTGTNG-3' core sequence. Transcriptional repressor. Members of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors, which includes Pegasus, are expressed in lymphocytes and are implicated in the control of lymphoid development.[supplied by OMIM, Jul 2002]
- ENST00000368886
- ENSP00000357881
- ENSG00000095574
- ENST00000617859
- ENSP00000478056
- ZNFN1A5
- PEGASUS
- ZNFN1A5
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
histone modification site profile | 0.86 | ||
virus perturbation | 0.59 | ||
small molecule perturbation | 0.58 | ||
transcription factor binding site profile | 0.54 | ||
transcription factor perturbation | 0.54 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2.84 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 54 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2.84 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 54 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 10
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0