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Tdark
IGFLR1
IGF-like family receptor 1

Protein Summary
Description
Probable cell membrane receptor for the IGF-like family proteins. Binds IGFL1 and IGFL3 with a higher affinity. May also bind IGFL2.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000246532
  • ENSP00000246532
  • ENSG00000126246
  • ENST00000592537
  • ENSP00000466181
  • ENST00000592889
  • ENSP00000467750

Symbol
  • TMEM149
  • U2AF1L4
  • TMEM149
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.84
small molecule perturbation
0.55
tissue sample
0.53
transcription factor binding site profile
0.53
cell line
0.51


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.1   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 100   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.1   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 100   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0