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Tbio
HSD11B1L
Hydroxysteroid 11-beta-dehydrogenase 1-like protein

Protein Summary
Description
This gene is a member of the hydroxysteroid dehydrogenase family. The encoded protein is similar to an enzyme that catalyzes the interconversion of inactive to active glucocorticoids (e.g. cortisone). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000301382
  • ENSP00000301382
  • ENSG00000167733
  • ENST00000339423
  • ENSP00000340436
  • ENST00000342970
  • ENSP00000343451
  • ENST00000411793
  • ENSP00000398955
  • ENST00000422535
  • ENSP00000409592
  • ENST00000423665
  • ENSP00000407154
  • ENST00000577917
  • ENSP00000463073
  • ENST00000581521
  • ENSP00000463794
  • ENST00000581773
  • ENSP00000462975
  • ENST00000581893
  • ENSP00000464454
  • ENST00000583928
  • ENSP00000462586

Symbol
  • HSD3
  • SCDR10
  • SDR26C2
  • HSD3
  • HSD1L
  • 11-DH3
  • SCDR10
  • SCDR10B
  • SDR26C2
  • 11-beta-HSD3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.69
protein domain
0.58
cell type or tissue
0.56
tissue sample
0.54
virus perturbation
0.5


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.33   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 101   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.33   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 101   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0